Title :

Virology and cell biology of the hepatitis C virus life cycle: an update.

Author(s) :

Dubuisson, Jean [Auteur correspondant]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
François-Loïc, Cosset [Auteur correspondant]
Virus enveloppés, vecteurs et immunothérapie – Enveloped viruses, Vectors and Immuno-therapy [EVIR]

Journal title :

Journal of Hepatology
Journal of Hepatology Update: Hepatitis C

Pages :

S3-S13

Publisher :

Elsevier

Publication date :

2014-10-31

ISSN :

0168-8278

English keyword(s) :

Hepatitis C virus
Viral life cycle
Virus entry
Virus-host interactions

HAL domain(s) :

Sciences du Vivant [q-bio]
Sciences du Vivant [q-bio]/Microbiologie et Parasitologie/Virologie
Sciences du Vivant [q-bio]/Médecine humaine et pathologie

English abstract : [en]

Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis and hepatocellular carcinoma. It imposes a serious problem to public health in the world as the population of chronically infected ...
Show more >Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis and hepatocellular carcinoma. It imposes a serious problem to public health in the world as the population of chronically infected HCV patients who are at risk of progressive liver disease is projected to increase significantly in the next decades. However, the arrival of new antiviral molecules is progressively changing the landscape of hepatitis C treatment. The search for new anti-HCV therapies has also been a driving force to better understand how HCV interacts with its host, and major progresses have been made on the various steps of the HCV life cycle. Here, we review the most recent advances in the fast growing knowledge on HCV life cycle and interaction with host factors and pathways.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Comment :

Affiliations ECOFECT

Collections :

• Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017

Source :

Harvested from HAL