Nonribosomal peptides and polyketides of ...
Type de document :
Compte-rendu et recension critique d'ouvrage
Titre :
Nonribosomal peptides and polyketides of Burkholderia: new compounds potentially implicated in biocontrol and pharmaceuticals
Auteur(s) :
Esmaeel, Qassim [Auteur]
LABORATOIRE DE STRESS, DÉFENSES ET REPRODUCTION DES PLANTES [SDRP]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Pupin, Maude [Auteur]
Bioinformatics and Sequence Analysis [BONSAI]
Université de Lille
Jacques, Philippe [Auteur]
Université de Liège
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Leclere, Valerie [Auteur correspondant]
Bioinformatics and Sequence Analysis [BONSAI]
Université de Lille
Institut Charles Viollette (ICV) - EA 7394 [ICV]
LABORATOIRE DE STRESS, DÉFENSES ET REPRODUCTION DES PLANTES [SDRP]
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Pupin, Maude [Auteur]

Bioinformatics and Sequence Analysis [BONSAI]
Université de Lille
Jacques, Philippe [Auteur]
Université de Liège
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Leclere, Valerie [Auteur correspondant]

Bioinformatics and Sequence Analysis [BONSAI]
Université de Lille
Institut Charles Viollette (ICV) - EA 7394 [ICV]
Titre de la revue :
Environmental Science and Pollution Research
Éditeur :
Springer Verlag
Date de publication :
2017
ISSN :
0944-1344
Mot(s)-clé(s) :
Lipopeptides
Siderophores
Siderophores
Mot(s)-clé(s) en anglais :
Burkholderia
NRPS
Hybrid NRPS
PKS
Biocontrol
NRPS
Hybrid NRPS
PKS
Biocontrol
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Sciences du Vivant [q-bio]/Biologie végétale
Sciences du Vivant [q-bio]/Biologie végétale
Résumé en anglais : [en]
Bacteria belonging to the genus Burkholderia live in various ecological niches and present a significant role in the environments through the excretion of a wide variety of secondary metabolites including modular nonribosomal ...
Lire la suite >Bacteria belonging to the genus Burkholderia live in various ecological niches and present a significant role in the environments through the excretion of a wide variety of secondary metabolites including modular nonribosomal peptides (NRPs) and polyketides (PKs). These metabolites represent a widely distributed biomedically and biocontrol important class of natural products including antibiotics, siderophores, and anticancers as well as biopesticides that are considered as a novel source that can be used to defend ecological niche from competitors and to promote plant growth. The aim of this review is to present all NRPs produced or potentially produced by strains of Burkholderia, as NRPs represent a major source of active compounds implicated in biocontrol. The review is a compilation of results from a large screening we have performed on 48 complete sequenced genomes available in NCBI to identify NRPS gene clusters, and data found in the literature mainly because some interesting compounds are produced by strains not yet sequenced. In addition to NRPs, hybrids NRPs/PKs are also included. Specific features about biosynthetic gene clusters and structures of the modular enzymes responsible for the synthesis, the biological activities, and the potential uses in agriculture and pharmaceutical of NRPs and hybrids NRPs/PKs will also be discussed.Lire moins >
Lire la suite >Bacteria belonging to the genus Burkholderia live in various ecological niches and present a significant role in the environments through the excretion of a wide variety of secondary metabolites including modular nonribosomal peptides (NRPs) and polyketides (PKs). These metabolites represent a widely distributed biomedically and biocontrol important class of natural products including antibiotics, siderophores, and anticancers as well as biopesticides that are considered as a novel source that can be used to defend ecological niche from competitors and to promote plant growth. The aim of this review is to present all NRPs produced or potentially produced by strains of Burkholderia, as NRPs represent a major source of active compounds implicated in biocontrol. The review is a compilation of results from a large screening we have performed on 48 complete sequenced genomes available in NCBI to identify NRPS gene clusters, and data found in the literature mainly because some interesting compounds are produced by strains not yet sequenced. In addition to NRPs, hybrids NRPs/PKs are also included. Specific features about biosynthetic gene clusters and structures of the modular enzymes responsible for the synthesis, the biological activities, and the potential uses in agriculture and pharmaceutical of NRPs and hybrids NRPs/PKs will also be discussed.Lire moins >
Langue :
Anglais
Vulgarisation :
Non
Collections :
Source :