Titre :

Pregnancy outcome in turner syndrome: a french multi-center study after the 2009 guidelines

Auteur(s) :

Cadoret, Florence [Auteur]
Parinaud, Jean [Auteur]
Bettiol, Celia [Auteur]
Pienkowski, Catherine [Auteur]
Letur, Helene [Auteur]
Ohl, Jeanine [Auteur]
Sentilhes, Loic [Auteur]
Papaxanthos, Aline [Auteur]
Winer, Norbert [Auteur]
Mathieu D''''argent, Emmanuelle [Auteur]
Jonard Catteau, Sophie [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172

Chauleur, Celine [Auteur]
Biquard, Florence [Auteur]
Hieronimus, Sylvie [Auteur]
Pimentel, Celine [Auteur]
Le Lous, Maela [Auteur]
Fontaine, Nathalie [Auteur]
Chevreau, Julien [Auteur]
Parant, Olivier [Auteur]

Titre de la revue :

European journal of obstetrics, gynecology, and reproductive biology

Nom court de la revue :

Eur. J. Obstet. Gynecol. Reprod. Biol.

Numéro :

229

Pagination :

20-25

Date de publication :

2018-08-03

ISSN :

1872-7654

Mot(s)-clé(s) :

Oocyte donation
Aortic diameter
Turner syndrome
Pregnancy

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

OBJECTIVE: This study aimed to assess the application of the French guidelines for pregnancies in Turner syndrome (TS) and their impact on perinatal prognosis. METHODS: We performed a French multi-center retrospective study ...
Lire la suite >OBJECTIVE: This study aimed to assess the application of the French guidelines for pregnancies in Turner syndrome (TS) and their impact on perinatal prognosis. METHODS: We performed a French multi-center retrospective study (14 centers), including TS pregnant patients (spontaneously or by Assisted Reproductive Technology (ART)) between January 2006 and July 2017. Only clinical pregnancies were analyzed. The adjustment of medical follow-up modalities to French guidelines was evaluated for all pregnancies after 2009. Pregnancies from oocyte donation (OD) after 2009 were compared to those of a cohort of TS pregnancies obtained by OD before 2009, which were reported by the French Study Group for Oocyte Donation. RESULTS: One hundred seventy pregnancies in 103 patients were included: 35 spontaneous, 5 by means of intra-conjugal ART, and 130 with OD. No serious maternal complications were observed. We reported two stillbirths and one intra uterine fetal death. The French guidelines were partially respected. The preconceptional assessment was carried out in 74% of cases. Cardiology follow-up during pregnancy was performed in accordance with guidelines in 74% of patients. Postpartum cardiac ultrasonography was performed in 45% of pregnancies but only in 11% within 8 days post-partum. When compared to the 2009 historical cohort, the rates of high blood pressure (19% vs. 38%; p < 0.005) pre-eclampsia (8% vs. 21%; p < 0.005) and prematurity <35 weeks (15% vs 38%; p < 0.0001) were lower. CONCLUSIONS: The implementation of guidelines has allowed the standardization of TS pregnancy care and improved perinatal indicators for both mothers and children. However, an effort must be done, in a postpartum survey.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Équipe(s) de recherche :

Développement et plasticité du cerveau neuro-endocrine

Date de dépôt :

2021-06-23T11:45:44Z