Title :

Compact multichannel spectroscopic label-free biosensor platform for plant diseases point-of-care testing (POCT)

Author(s) :

Hastanin, Jurij [Auteur]
Université de Liège
Lenaerts, Cedric [Auteur]
Université de Liège
Gailly, Patrick [Auteur]
Université de Liège
Rabecki, Frédéric [Auteur]
Université de Liège
Roobroeck, Aline [Auteur]
Materia Nova Research Center [MNRC]
Desprez, Sylvain [Auteur]
Materia Nova Research Center [MNRC]
Bernier, Damien [Auteur]
Multitel Asbl
Dortu, Fabian [Auteur]
Multitel Asbl
Dekuijper, Camille [Auteur]
Lanterbecq, Deborah [Auteur]
Lecointe, Karine [Auteur]
Institut de Pathologie [CHU Lille]
Sendid, Boualem [Auteur]
Institut de Pathologie [CHU Lille]
Bouazaoui, Mohamed [Auteur]
Laboratoire de Physique des Lasers, Atomes et Molécules - UMR 8523 [PhLAM]
Maricot, Sophie [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Optoélectronique - IEMN [OPTO - IEMN]
Bakouche, Mohamed-Taieb [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Ganesan, Sivaramakrishnan [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Vilcot, Jean-Pierre [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Optoélectronique - IEMN [OPTO - IEMN]
Fleury-Frenette, Karl [Auteur]
Université de Liège

Conference title :

SPIE Photonics Europe, Conference 11361 - Biophotonics: Biophotonics in Point-of-Care

City :

Online Only

Country :

France

Start date of the conference :

2020-04-06

Book title :

Proceedings of the SPIE - International Society for Optical Engineering, Volume 11361, Biophotonics in Point-of-Care; 113610P

Publisher :

SPIE

Publication date :

2020

English keyword(s) :

Sensors
Refractive index
Microfluidics
Molecules
Biosensing
Plasmonics
Biological research

HAL domain(s) :

Sciences de l'ingénieur [physics]
Sciences de l'ingénieur [physics]/Optique / photonique

English abstract : [en]

The POCT technology involving low cost Lab-On-Chip label-free biosensing opens up an opportunity to drastically reduce the total cost of plant health and disease monitoring tools. The main requirement for a POCT tool is ...
Show more >The POCT technology involving low cost Lab-On-Chip label-free biosensing opens up an opportunity to drastically reduce the total cost of plant health and disease monitoring tools. The main requirement for a POCT tool is that it should involve relatively inexpensive equipment ensuring a sufficiently high accuracy of the plant disease early diagnostic. The principal objective of the presented work was to develop of a cost effective tool for biosensing assay, easy to use even for unskilled user. The label-free biosensing involving an optical near-field resonance phenomenon, such as Surface Plasmon Resonance (SPR) or localized surface plasmon resonance (LSPR), appears to be an appropriate approach for the above requirements. In this paper, we present a concept of multichannel biosensing platform dedicated to POCT, as well as the first proof-of-concept experimental investigations, demonstrating its practical feasibility. The instrumental platform investigated by our research group includes both disposable multichannel biochip and spectroscopic optical readout device. The proposed approach gives access to two plasmonic detection formats on the same lab-on-chip device: SPR and LSPR biosensing. In order to implement the LSPR sensing approach, our team has developed an original microfabrication method involving gold nanoparticles (Au_NPs) synthesis by pulsed laser writing. The biochip includes both microfluidic and biosensor structures formed into a single plastic slab.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Institut d'Électronique, de Microélectronique et de Nanotechnologie (IEMN) - UMR 8520

Source :

Harvested from HAL