Laryngotracheal anomalies associated with ...
Document type :
Article dans une revue scientifique
PMID :
Permalink :
Title :
Laryngotracheal anomalies associated with esophageal atresia: importance of early diagnosis
Author(s) :
Fayoux, Pierre [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Sfeir, Rony [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Michaud, Laurent [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Daniel, Sam [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Sfeir, Rony [Auteur]
Environnement périnatal et croissance - EA 4489 [EPS]
Michaud, Laurent [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Daniel, Sam [Auteur]
Journal title :
European Archives of Oto-Rhino-Laryngology
Abbreviated title :
Eur. Arch. Oto-Rhino-Laryn.
Volume number :
275
Pages :
477-481
Publication date :
2018-02
ISSN :
0937-4477
Keyword(s) :
Endoscopy
Laryngotracheal anomalies
Esophageal atresia
Laryngeal cleft
Surgery
Laryngotracheal anomalies
Esophageal atresia
Laryngeal cleft
Surgery
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Objective: Esophageal atresia (EA) is the most common congenital esophageal malformation. Airway pathology, in particular, tracheomalacia and laryngotracheal anomalies is a major cause of morbidity and mortalilty in patients ...
Show more >Objective: Esophageal atresia (EA) is the most common congenital esophageal malformation. Airway pathology, in particular, tracheomalacia and laryngotracheal anomalies is a major cause of morbidity and mortalilty in patients with EA. The aim of this study was to report the incidence and type of laryngotracheal anomalies seen in a large series of patients with EA, and to evaluate their impact on the management of children with EA. Study design: Retrospective study. Materials and methods: Retrospective cohort including all patients referred to the EA National Reference Center from January 2002 to December 2014. Airway assessment was based on endoscopy performed before, during and/or after esophageal surgery. Results: One-hundred and fifty-eight patients were included in the study. Endoscopy revealed tracheomalacia in 141 cases (89.2%) and other laryngotracheal anomalies in 43 patients (27.2%). Ninety-six patients (60.7%) presented with persistent respiratory symptoms, including acute life-threatening events in 21 cases, leading to death in 6 cases. A correlation was observed between degree of tracheal collapse and presence of acute life-threatening events. Laryngotracheal surgery was required in 35 cases (22%). Conclusion: Laryngotracheal anomalies are frequently associated with EA and represent an important etiology of morbidity and mortality that can be prevented by early and systematic diagnosis and aggressive management. An early systematic endoscopic evaluation is recommended to coordinate the airway management with the EA surgery.Show less >
Show more >Objective: Esophageal atresia (EA) is the most common congenital esophageal malformation. Airway pathology, in particular, tracheomalacia and laryngotracheal anomalies is a major cause of morbidity and mortalilty in patients with EA. The aim of this study was to report the incidence and type of laryngotracheal anomalies seen in a large series of patients with EA, and to evaluate their impact on the management of children with EA. Study design: Retrospective study. Materials and methods: Retrospective cohort including all patients referred to the EA National Reference Center from January 2002 to December 2014. Airway assessment was based on endoscopy performed before, during and/or after esophageal surgery. Results: One-hundred and fifty-eight patients were included in the study. Endoscopy revealed tracheomalacia in 141 cases (89.2%) and other laryngotracheal anomalies in 43 patients (27.2%). Ninety-six patients (60.7%) presented with persistent respiratory symptoms, including acute life-threatening events in 21 cases, leading to death in 6 cases. A correlation was observed between degree of tracheal collapse and presence of acute life-threatening events. Laryngotracheal surgery was required in 35 cases (22%). Conclusion: Laryngotracheal anomalies are frequently associated with EA and represent an important etiology of morbidity and mortality that can be prevented by early and systematic diagnosis and aggressive management. An early systematic endoscopic evaluation is recommended to coordinate the airway management with the EA surgery.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Inserm
Université de Lille
CHU Lille
Université de Lille
CHU Lille
Collections :
Research team(s) :
Nutritional modulation of inflammation and infection
Submission date :
2019-03-01T15:24:44Z
2021-05-20T15:27:59Z
2023-12-13T11:00:12Z
2021-05-20T15:27:59Z
2023-12-13T11:00:12Z