Title :

[Review] The role of the surface ligand on the performance of electrochemical SARS-CoV-2 antigen biosensors

Author(s) :

Szunerits, Sabine [Auteur]
NanoBioInterfaces - IEMN [NBI - IEMN]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Pagneux, Quentin [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Swaidan, Abir [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Mishyn, Vladyslav [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Roussel, Alain [Auteur]
Architecture et fonction des macromolécules biologiques [AFMB]
Cambillau, Christian [Auteur]
Architecture et fonction des macromolécules biologiques [AFMB]
Devos, David [Auteur]
Lille Neurosciences & Cognition - U 1172 [LilNCog]
Engelmann, Ilka [Auteur]
Centre d'Immunologie de Marseille - Luminy [CIML]
Alidjinou, Enagnon Kazali [Auteur]
Laboratoire de Virologie - ULR 3610 [Laboratoire de Virologie]
Happy, Henri [Auteur]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]
Carbon - IEMN [CARBON - IEMN]
Boukherroub, Rabah [Auteur]
NanoBioInterfaces - IEMN [NBI - IEMN]
Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 [IEMN]

Journal title :

Analytical and Bioanalytical Chemistry

Pages :

pp 103–113

Publisher :

Springer Verlag

Publication date :

2022-01

ISSN :

1618-2642

English keyword(s) :

biosensors
electrochemistry
field effect transistors
point-of-care (poc) technologies
sars-cov-2
surface ligands

HAL domain(s) :

Sciences de l'ingénieur [physics]

English abstract : [en]

Point-of-care (POC) technologies and testing programs hold great potential to significantly improve diagnosis and disease surveillance. POC tests have the intrinsic advantage of being able to be performed near the patient ...
Show more >Point-of-care (POC) technologies and testing programs hold great potential to significantly improve diagnosis and disease surveillance. POC tests have the intrinsic advantage of being able to be performed near the patient or treatment facility, owing to their portable character. With rapid results often in minutes, these diagnostic platforms have a high positive impact on disease management. POC tests are, in addition, advantageous in situations of a shortage of skilled personnel and restricted availability of laboratory-based analytics. While POC testing programs are widely considered in addressing health care challenges in low-income health systems, the ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections could largely benefit from fast, efficient, accurate, and cost-effective point-of-care testing (POCT) devices for limiting COVID-19 spreading. The unrestrained availability of SARS-CoV-2 POC tests is indeed one of the adequate means of better managing the COVID-19 outbreak. A large number of novel and innovative solutions to address this medical need have emerged over the last months. Here, we critically elaborate the role of the surface ligands in the design of biosensors to cope with the current viral outbreak situation. Their notable effect on electrical and electrochemical sensors' design will be discussed in some given examples.Show less >

Language :

Anglais

Popular science :

Non

ANR Project :

Infrastructure Française pour la Biologie Structurale Intégrée
Dispositive portable de diagnostic pour différencier le virus la grippe de celui de Covid-19

Collections :

• Institut d'Électronique, de Microélectronique et de Nanotechnologie (IEMN) - UMR 8520

Source :

Harvested from HAL