Title :

TRI-SCORE: a new risk score for in-hospital mortality prediction after isolated tricuspid valve surgery

Author(s) :

Dreyfus, Julien [Auteur]
Centre cardiologique du Nord [CCN]
Audureau, Etienne [Auteur]
Institut Mondor de Recherche Biomédicale [IMRB]
IMRB - CEPIA/"Clinical Epidemiology And Ageing : Geriatrics, Primary Care and Public Health" [Créteil] [U955 Inserm - UPEC]
Bohbot, Yohann [Auteur]
Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 [MP3CV]
Coisne, Augustin [Auteur]
Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires [RNMCD - U1011]
Lavie-Badie, Yoan [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Bouchery, Maxime [Auteur]
CHU Henri Mondor [Créteil]
Flagiello, Michele [Auteur]
Hôpital Louis Pradel [CHU - HCL]
Bazire, Baptiste [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Eggenspieler, Florian [Auteur]
Centre Hospitalier Régional Universitaire de Nancy [CHRU Nancy]
Viau, Florence [Auteur]
Riant, Elisabeth [Auteur]
Centre cardiologique du Nord [CCN]
Mbaki, Yannick [Auteur]
CHU Pontchaillou [Rennes]
Laboratoire Traitement du Signal et de l'Image [LTSI]
Eyharts, Damien [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Senage, Thomas [Auteur]
Centre hospitalier universitaire de Nantes [CHU Nantes]
Modine, Thomas [Auteur]
Nicol, Martin [Auteur]
Centre cardiologique du Nord [CCN]
Doguet, Fabien [Auteur]
Endothélium, valvulopathies et insuffisance cardiaque [EnVI]
Nguyen, Virginia [Auteur]
Centre cardiologique du Nord [CCN]
Le Tourneau, Thierry [Auteur]
Centre hospitalier universitaire de Nantes [CHU Nantes]
Tribouilloy, Christophe [Auteur]
Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 [MP3CV]
Donal, Erwan [Auteur]
CHU Pontchaillou [Rennes]
Laboratoire Traitement du Signal et de l'Image [LTSI]
Tomasi, Jacques [Auteur]
CHU Pontchaillou [Rennes]
Habib, Gilbert [Auteur]
Microbes évolution phylogénie et infections [MEPHI]
Selton-Suty, Christine [Auteur]
Service de Cardiologie [CHRU Nancy]
Raffoul, Richard [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Iung, Bernard [Auteur]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Obadia, Jean-François [Auteur]
Hôpital Louis Pradel [CHU - HCL]
Messika-Zeitoun, David [Auteur]
University of Ottawa [Ottawa]

Journal title :

European Heart Journal

Pages :

654-662

Publisher :

Oxford University Press (OUP)

Publication date :

2022-02-12

ISSN :

0195-668X

English keyword(s) :

Outcome
Surgery
Tricuspid regurgitation
Risk score

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

AIMS : Isolated tricuspid valve surgery (ITVS) is considered to be a high-risk procedure, but in-hospital mortality is markedly variable. This study sought to develop a dedicated risk score model to predict the outcome of ...
Show more >AIMS : Isolated tricuspid valve surgery (ITVS) is considered to be a high-risk procedure, but in-hospital mortality is markedly variable. This study sought to develop a dedicated risk score model to predict the outcome of patients after ITVS for severe tricuspid regurgitation (TR). METHODS AND RESULTS : All consecutive adult patients who underwent ITVS for severe non-congenital TR at 12 French centres between 2007 and 2017 were included. We identified 466 patients (60 ± 16 years, 49% female, functional TR in 49%). In-hospital mortality rate was 10%. We derived and internally validated a scoring system to predict in-hospital mortality using multivariable logistic regression and bootstrapping with 1000 re-samples. The final risk score ranged from 0 to 12 points and included eight parameters: age ≥70 years, New York Heart Association Class III-IV, right-sided heart failure signs, daily dose of furosemide ≥125 mg, glomerular filtration rate <30 mL/min, elevated bilirubin, left ventricular ejection fraction <60%, and moderate/severe right ventricular dysfunction. Tricuspid regurgitation mechanism was not an independent predictor of outcome. Observed and predicted in-hospital mortality rates increased from 0% to 60% and from 1% to 65%, respectively, as the score increased from 0 up to ≥9 points. Apparent and bias-corrected areas under the receiver operating characteristic curves were 0.81 and 0.75, respectively, much higher than the logistic EuroSCORE (0.67) or EuroSCORE II (0.63). CONCLUSION : We propose TRI-SCORE as a dedicated risk score model based on eight easy to ascertain parameters to inform patients and physicians regarding the risk of ITVS and guide the clinical decision-making process of patients with severe TR, especially as transcatheter therapies are emerging (www.tri-score.com).Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (EGID) - U1011

Source :

Harvested from HAL