Titre :

Physico-chemical characterization and in vitro inflammatory and oxidative potency of atmospheric particles collected in dakar city''s (senegal)

Auteur(s) :

Ndong Ba, Awa [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Cazier, Fabrice [Auteur]
Centre commun de mesures [CCM-ULCO]
Verdin, Anthony [Auteur]
Garçon, Guillaume [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Cabral, Mathilde [Auteur]
Université Cheikh Anta Diop de Dakar [Sénégal] [UCAD]
Courcot, Lucie [Auteur]
Laboratoire d'Océanologie et de Géosciences (LOG) - UMR 8187
Diouf, Amadou [Auteur]
Université Cheikh Anta Diop de Dakar [Sénégal] [UCAD]
Courcot, Dominique [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Gualtieri, Maurizio [Auteur]
Unité de Chimie Environnementale et Interactions sur le Vivant [UCEIV]
Fall, Mamadou [Auteur]
Université Cheikh Anta Diop de Dakar [Sénégal] [UCAD]

Titre de la revue :

Environmental pollution (Barking, Essex . 1987)

Nom court de la revue :

Environ. Pollut.

Numéro :

245

Pagination :

568-581

Éditeur :

Elsevier

Date de publication :

2018-11-12

ISSN :

1873-6424

Mot(s)-clé(s) :

Physicochemical characterization
PM2.5
PM > 2.5
Air pollution
BEAS-2B cells
Inflammatory response
Oxidative damages

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Exposure to atmospheric pollutants has been recognized as a major risk factor of respiratory and cardiovascular diseases. Fine particles (PM2.5) and a coarser fraction (PM>2.5) sampled at an urban site in Dakar (HLM), ...
Lire la suite >Exposure to atmospheric pollutants has been recognized as a major risk factor of respiratory and cardiovascular diseases. Fine particles (PM2.5) and a coarser fraction (PM>2.5) sampled at an urban site in Dakar (HLM), characterized by high road traffic emissions, were compared with particles sampled at a rural area, Toubab Dialaw located about 40 km from Dakar. The physicochemical characteristics of samples revealed that PMs differ for their physical (surface area) and chemical properties (in terms of CHN, metals, ions, paraffins, VOCs and PAHs) that were 65–75% higher in urban samples. Moreover the fine PMs contain higher amounts of anthropogenic related pollutants than the PM>2.5 one. These differences are sustained by the ratios reported for the analysed PAHs which suggest as predominant primary emission sources vehicle exhausts at urban site and biomass combustion at the rural site. The inflammatory response and the oxidative damages were evaluated in BEAS-2B cells by the quantification of 4 selected inflammatory cytokines (TNF-α, IL-1β, IL-6, IL-8) and of total carbonylated proteins and the oxidative DNA adduct 8-OHdG after 8 or 24 h exposure. In accordance with the different sources and different physical and chemical properties, the inflammatory response and the oxidative damages were found higher in bronchial cells exposed to urban PMs. These data confirm the importance, also for West African countries, to evaluate the correlation between PM physico-chemical properties and potential biological impacts.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
CNRS
Institut Pasteur de Lille
Univ. Littoral Côte d’Opale
Université de Lille

Collections :

• IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
• Laboratoire d'Océanologie et de Géosciences (LOG) - UMR 8187

Date de dépôt :

2022-02-02T10:23:50Z
2024-03-13T10:01:27Z