Cheminformatics driven development of novel ...

Document type :
Article dans une revue scientifique: Article original
DOI :
10.1002/minf.201800043
PMID :
29733509
Permalink :
http://hdl.handle.net/20.500.12210/75084
Title :
Cheminformatics driven development of novel therapies for drug resistant prostate cancer
Author(s) :
Ban, Fuqiang [Auteur]
Dalal, Kush [Auteur]
Leblanc, Eric [Auteur] refId
Morin, Helene [Auteur]
Rennie, Paul S. [Auteur]
Cherkasov, Artem [Auteur]
Journal title :
Molecular informatics
Abbreviated title :
Mol Inform
Publication date :
2018-05-07
ISSN :
1868-1751
Keyword(s) :
drug resistance
prostate cancer
Androgen receptor
cheminformatics
antiandrogen
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Androgen receptor (AR) is a master regulator of prostate cancer (PCa), and therefore is a pivotal drug target for the treatment of PCa including its castration-resistance form (CRPC). The development of acquired resistance ...
Show more >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
INSERM
Université de Lille
Collections :
Submission date :
2022-06-15T13:58:38Z