Title :

Glioblastoma in adults: a society for neuro-oncology (sno) and european society of neuro-oncology (eano) consensus review on current management and future directions

Author(s) :

Wen, Patrick Y. [Auteur]
Weller, Michael [Auteur]
Lee, Eudocia Quant [Auteur]
Alexander, Brian A. [Auteur]
Barnholtz-Sloan, Jill S. [Auteur]
Barthel, Floris P. [Auteur]
Batchelor, T. T. [Auteur]
Bindra, Ranjit S. [Auteur]
Chang, Susan M. [Auteur]
Chiocca, E. Antonio [Auteur]
Cloughesy, Timothy F. [Auteur]
De Groot, John F. [Auteur]
Galanis, Evanthia [Auteur]
Gilbert, Mark R. [Auteur]
Hegi, Monika E. [Auteur]
Horbinski, Craig [Auteur]
Huang, Raymond Y. [Auteur]
Lassman, Andrew B. [Auteur]
Le Rhun, Emilie [Auteur]
Lim, Michael [Auteur]
Mehta, Minesh P. [Auteur]
Mellinghoff, Ingo K. [Auteur]
Minniti, Giuseppe [Auteur]
Nathanson, David [Auteur]
Platten, Michael [Auteur]
Preusser, Matthias [Auteur]
Roth, Patrick [Auteur]
Sanson, Marc [Auteur]
Schiff, David [Auteur]
Short, Susan C. [Auteur]
Taphoorn, Martin J. B. [Auteur]
Tonn, Jorg-Christian [Auteur]
Tsang, Jonathan [Auteur]
Verhaak, Roel G. W. [Auteur]
Von Deimling, Andreas [Auteur]
Wick, Wolfgang [Auteur]
Zadeh, Gelareh [Auteur]
Reardon, David A. [Auteur]
Aldape, Kenneth D. [Auteur]
Van Den Bent, Martin J. [Auteur]

Journal title :

Neuro-Oncology

Abbreviated title :

Neuro-oncology

Publication date :

2020-04-24

ISSN :

1523-5866

Keyword(s) :

therapy
clinical trials
diagnosis
glioblastoma

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Glioblastomas are the most common form of malignant primary brain tumor and an important cause of morbidity and mortality. In recent years there have been important advances in understanding the molecular pathogenesis and ...
Show more >Glioblastomas are the most common form of malignant primary brain tumor and an important cause of morbidity and mortality. In recent years there have been important advances in understanding the molecular pathogenesis and biology of these tumors, but this has not translated into significantly improved outcomes for patients. In this consensus review from the Society for Neuro-Oncology (SNO) and the European Association of Neuro-Oncology (EANO), the current management of isocitrate dehydrogenase wildtype (IDHwt) glioblastomas will be discussed. In addition, novel therapies such as targeted molecular therapies, agents targeting DNA damage response and metabolism, immunotherapies, and viral therapies will be reviewed, as well as the current challenges and future directions for research.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

INSERM
Université de Lille

Collections :

• Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192

Submission date :

2022-06-15T13:59:55Z