Title :

Compared impact of diabetes on the risk of heart failure from acute myocardial infarction to chronic coronary artery disease

Author(s) :

Lemesle, Gilles [Auteur]
Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires [RNMCD - U1011]
Centre Hospitalier Régional Universitaire [Lille] [CHRU Lille]
Puymirat, Etienne [Auteur]
Hôpital Européen Georges Pompidou [APHP] [HEGP]
Paris-Centre de Recherche Cardiovasculaire [PARCC (UMR_S 970/ U970)]
Bonello, Laurent [Auteur]
Hôpital Nord [CHU - APHM]
Mediterranean Association for Research and Studies in Cardiology [MARS cardio]
Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research [C2VN]
Simon, Tabassome [Auteur]
Université Sorbonne Paris Nord
Steg, Philippe-Gabriel [Auteur]
Alliance française pour les essais cliniques cardio-vasculaires - French Alliance for Cardiovascular Trials [FACT]
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Ferrières, Jean [Auteur]

Centre d'Epidémiologie et de Recherche en santé des POPulations [CERPOP]
Schiele, François [Auteur]
European Atherosclerosis Society [Göteborg, Sweden] [EAS]
Fauchier, Laurent [Auteur]
Éducation Éthique Santé EA 7505 [EES]
CHU Trousseau [Tours]
Henry, Patrick [Auteur]
Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris]
Schurtz, Guillaume [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Ninni, Sandro [Auteur]
Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires [RNMCD - U1011]
Centre Hospitalier Régional Universitaire [Lille] [CHRU Lille]
Lamblin, Nicolas [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Bauters, Christophe [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Danchin, Nicolas [Auteur]
Hôpital Européen Georges Pompidou [APHP] [HEGP]

Journal title :

Diabetes & Metabolism

Pages :

101265

Publisher :

Elsevier Masson

Publication date :

2022-01

ISSN :

1262-3636

English keyword(s) :

Coronary artery disease
Diabetes mellitus
Heart failure
Myocardial infarction

HAL domain(s) :

Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Endocrinologie et métabolisme

English abstract : [en]

Aim: We attempted to describe the risk of heart failure (HF) occurrence according to diabetes mellitus (DM) status in patients with coronary artery disease (CAD) over time, from acute myocardial infarction (MI) to the ...
Show more >Aim: We attempted to describe the risk of heart failure (HF) occurrence according to diabetes mellitus (DM) status in patients with coronary artery disease (CAD) over time, from acute myocardial infarction (MI) to the chronic stable phase. Methods: For the acute and subacute MI phases, we analysed the FAST-MI cohort restricted to patients with -out history of HF (n = 12,473). The analysis on 1-year outcomes after MI was further restricted to patients who were discharged alive and without history of HF and/or HF symptoms during the index hospitalisation for MI (n = 9181). To analyse the chronic phase, we analysed the CORONOR cohort restricted to patients with -out history of HF (n = 3871). The primary endpoint was HF occurrence according to DM status. We also ana-lysed the composite of all-cause death or HF. Results: Killip-Kimball class >= II during the index MI hospitalisation was more frequent in DM patients com-pared to non-DM patients (29% vs. 15.3%, adjusted OR = 1.60). At one year after MI, hospitalisation for HF was more frequent in DM patients (3.3% vs. 1.2%, adjusted HR = 1.73). At the chronic phase (5-year outcomes), hospitalisation for HF was more frequent in DM patients (8.5% vs. 4.3%, adjusted HR = 1.70). Results focusing on the composite endpoint (all-cause death or HF) were consistent. Conclusion: DM was associated with a very constant near 2-fold increase in the risk of HF whatever the pre-sentation of CAD. Avoiding the risk of HF occurrence in CAD patients with DM is critical in daily practice and should be a constant life-long endeavour.Show less >

Language :

Anglais

Peer reviewed article :

Oui

Audience :

Internationale

Popular science :

Non

Collections :

• Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (EGID) - U1011

Source :

Harvested from HAL