Evaluation of blood pressure lowering ...
Document type :
Article dans une revue scientifique: Article original
Permalink :
Title :
Evaluation of blood pressure lowering effects of cocoa flavanols in diabetes mellitus: A systematic review and meta-analysis
Author(s) :
Tanghe, Anouk [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Heyman, Elsa [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Vanden Wyngaert, Karsten [Auteur]
Universiteit Gent = Ghent University [UGENT]
Van Ginckel, Ans [Auteur]
Universiteit Gent = Ghent University [UGENT]
Celie, Bert [Auteur]
Universiteit Gent = Ghent University [UGENT]
Rietzschel, Ernst [Auteur]
Universiteit Gent = Ghent University [UGENT]
Calders, Patrick [Auteur]
Universiteit Gent = Ghent University [UGENT]
Shadid, Samyah [Auteur]
Universiteit Gent = Ghent University [UGENT]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Heyman, Elsa [Auteur]
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Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Vanden Wyngaert, Karsten [Auteur]
Universiteit Gent = Ghent University [UGENT]
Van Ginckel, Ans [Auteur]
Universiteit Gent = Ghent University [UGENT]
Celie, Bert [Auteur]
Universiteit Gent = Ghent University [UGENT]
Rietzschel, Ernst [Auteur]
Universiteit Gent = Ghent University [UGENT]
Calders, Patrick [Auteur]
Universiteit Gent = Ghent University [UGENT]
Shadid, Samyah [Auteur]
Universiteit Gent = Ghent University [UGENT]
Journal title :
journal of functional foods
Abbreviated title :
Journal of Functional Foods
Volume number :
79
Pages :
104399
Publisher :
Elsevier BV
Publication date :
2021-04
ISSN :
1756-4646
HAL domain(s) :
Sciences du Vivant [q-bio]
Sciences du Vivant [q-bio]
Sciences du Vivant [q-bio]
English abstract : [en]
In healthy people, cocoa-derived flavanols (CF) improve blood pressure (BP). This meta-analysis investigates whether CF also affect BP in diabetic patients. PubMed, Web of Science, and Embase were consulted to retrieve ...
Show more >In healthy people, cocoa-derived flavanols (CF) improve blood pressure (BP). This meta-analysis investigates whether CF also affect BP in diabetic patients. PubMed, Web of Science, and Embase were consulted to retrieve eligible randomized controlled trials. A random-effects model and the Grades of Recommendation, Assessment, Development and Evaluation (GRADE)-approach were used for analyses and quality of evidence respectively. Of 267 citations, 11 trials were identified, studying either type 2 diabetic populations only (subgroup A) or type 2 diabetic patients plus non-diabetic subjects with increased cardiovascular risk (subgroup B1) or type 1 plus type 2 diabetic patients (subgroup B2). Mid/long-term CF consumption decreased BP slightly, however, only reaching statistical significance for diastolic BP in subgroup B1 (-1.89 mmHg, 95% CI: − 3.24, − 0.54, I2 = 55%). Considerable heterogeneity between studies and low quality of evidence caused poor quality evidence of minimal effects of CF ingestion on BP in diabetic patients.Show less >
Show more >In healthy people, cocoa-derived flavanols (CF) improve blood pressure (BP). This meta-analysis investigates whether CF also affect BP in diabetic patients. PubMed, Web of Science, and Embase were consulted to retrieve eligible randomized controlled trials. A random-effects model and the Grades of Recommendation, Assessment, Development and Evaluation (GRADE)-approach were used for analyses and quality of evidence respectively. Of 267 citations, 11 trials were identified, studying either type 2 diabetic populations only (subgroup A) or type 2 diabetic patients plus non-diabetic subjects with increased cardiovascular risk (subgroup B1) or type 1 plus type 2 diabetic patients (subgroup B2). Mid/long-term CF consumption decreased BP slightly, however, only reaching statistical significance for diastolic BP in subgroup B1 (-1.89 mmHg, 95% CI: − 3.24, − 0.54, I2 = 55%). Considerable heterogeneity between studies and low quality of evidence caused poor quality evidence of minimal effects of CF ingestion on BP in diabetic patients.Show less >
Peer reviewed article :
Oui
Audience :
Internationale
Administrative institution(s) :
Université de Lille
Univ. Artois
Univ. Littoral Côte d’Opale
Univ. Artois
Univ. Littoral Côte d’Opale
Research team(s) :
Activité Physique, Muscle, Santé (APMS)
Submission date :
2023-03-16T20:23:02Z
2023-03-29T06:46:47Z
2023-03-29T06:46:47Z
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