Titre :

Influence of nocturnal hypoxemia on follow-up course after type B acute aortic syndrome

Auteur(s) :

Delsart, Pascal [Auteur]
Soquet, Jerome [Auteur]
Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U 1011 [RNMCD]
Pierache, Adeline [Auteur]
Dedeken, Maxime [Auteur]
Fry, Stephanie [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Mallart, Anne [Auteur]
Pontana, Francois [Auteur]
Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 [RNMCD]
Azzaoui, Richard [Auteur]
Institut Coeur Poumon [CHU Lille]
Juthier, Francis [Auteur]
Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 [RNMCD]
Sobocinski, Jonathan [Auteur]
Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 [MBLC - ADDS]
Mounier Vehier, Claire [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Institut Coeur Poumon [CHU Lille]

Titre de la revue :

BMC Pulmonary Medicine

Pagination :

401

Éditeur :

BioMed Central

Date de publication :

2021-12-10

ISSN :

1471-2466

Mot(s)-clé(s) :

Prognosis
Sleep apnea
Nocturnal hypoxemia
Aortic dissection

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

IntroductionAssociation between sleep nocturnal breathing disorders and acute aortic syndrome (AAS) has been described but mid-term data are scarce.ObjectivesWe assessed the prognostic value of sleep apnea parameters and ...
Lire la suite >IntroductionAssociation between sleep nocturnal breathing disorders and acute aortic syndrome (AAS) has been described but mid-term data are scarce.ObjectivesWe assessed the prognostic value of sleep apnea parameters and their relationship with aortic morphology after the onset of a type B AAS.MethodsBetween January 2010 and January 2018, sleep apnea screening in post type B AAS was prospectively performed. The association of sleep apnea parameters with aortic morphology and aortic expansion during follow-up was studied.ResultsOver the 8-year-study period, 103 patients were included, with a mean age of 57.8 ± 12.1 years old. Median follow-up was 25.0 months (11.0–51.0). Thirty-two patients (31%) required aortic stenting during the acute phase. In patients treated by aortic stenting, the descending thoracic aortic diameter was positively associated with a higher percentage of nocturnal time of saturation ≤ 90% after adjustment (p = 0.016). During follow-up, the nocturnal time of saturation ≤ 90% in patients treated by medical therapy was the only parameter associated with significant aortic expansion rate (r = 0.26, p = 0.04). Thirty-eight patients started and sustained nocturnal ventilation during follow-up. The association between aortic expansion rate and nocturnal time of saturation ≤ 90% did not persist during follow-up after adjustment on nocturnal ventilation initiation (r = 0.25, p = 0.056).ConclusionsNocturnal hypoxemia parameters are positively associated with the max onset aortic diameter and significant aortic growth after type B AAS. Nocturnal ventilation seems to mitigate aortic expansion during follow-up.Lire moins >

Langue :

Anglais

Comité de lecture :

Oui

Audience :

Internationale

Vulgarisation :

Non

Collections :

• Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (RNMCD) - U1011

Source :

Harvested from HAL