Titre :

No evidence that spice consumption is a cancer prevention mechanism in human populations

Auteur(s) :

Dujon, Antoine [Auteur]
Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle [MIVEGEC]
Centre de Recherches Ecologiques et Evolutives sur le Cancer [MIVEGEC-CREEC]
Deakin University [Waurn Ponds]
Tasiemski, Aurélie [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Pujol, Pascal [Auteur]
Centre Hospitalier Régional Universitaire [Montpellier] [CHRU Montpellier]
Centre de Recherches Ecologiques et Evolutives sur le Cancer [MIVEGEC-CREEC]
Turpin, Anthony [Auteur]
Hétérogénéité, Plasticité et Résistance aux Thérapies des Cancers = Cancer Heterogeneity, Plasticity and Resistance to Therapies - UMR 9020 - U 1277 [CANTHER]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Ujvari, Beata [Auteur]
Centre de Recherches Ecologiques et Evolutives sur le Cancer [MIVEGEC-CREEC]
Deakin University [Waurn Ponds]
Thomas, Frédéric [Auteur]
Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle [MIVEGEC]
Centre de Recherches Ecologiques et Evolutives sur le Cancer [MIVEGEC-CREEC]

Titre de la revue :

Evolution, Medicine, and Public Health

Pagination :

45 - 52

Éditeur :

Oxford : Oxford University Press

Date de publication :

2022-11-24

ISSN :

2050-6201

Mot(s)-clé(s) en anglais :

Behaviour
Oncogenes
Prophylaxy

Discipline(s) HAL :

Sciences du Vivant [q-bio]/Santé publique et épidémiologie
Sciences du Vivant [q-bio]/Alimentation et Nutrition
Sciences du Vivant [q-bio]/Cancer

Résumé en anglais : [en]

Background: Why humans historically began to incorporate spices into their diets is still a matter of unresolved debate. For example, a recent study (Bromham et al. There is little evidence that spicy food in hot countries ...
Lire la suite >Background: Why humans historically began to incorporate spices into their diets is still a matter of unresolved debate. For example, a recent study (Bromham et al. There is little evidence that spicy food in hot countries is an adaptation to reducing infection risk. Nat Hum Behav 2021;5:878-91.) did not support the most popular hypothesis that spice consumption was a practice favoured by selection in certain environments to reduce food poisoning, parasitic infections, and foodborne diseases.Methods: Because several spices are known to have anticancer effects, we explored the hypothesis that natural selection and/or cultural evolution may have favoured spice consumption as an adaptive prophylactic response to reduce the burden of cancer pathology. We used linear models to investigate the potential relationship between age-standardized gastrointestinal cancer rates and spice consumption in 36 countries.Results: Patterns of spice are not consistent with a cancer mitigation mechanism: the age-standardized rate of almost all gastrointestinal cancers was not related to spice consumption.Conclusions: Direction other than foodborne pathogens and cancers should be explored to understand the health reasons, if any, why our ancestors developed a taste for spices.Lire moins >

Langue :

Anglais

Comité de lecture :

Oui

Audience :

Internationale

Vulgarisation :

Non

Projet ANR :

ECOLOGIE ET EVOLUTION DES CANCERS TRANSMISSIBLES

Collections :

• Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 9017

Source :

Harvested from HAL