Title :

Incidence and predictors of mortality after an electrical storm in the ICU

Author(s) :

Ninni, Sandro [Auteur]
Layec, Jeremy [Auteur]
Brigadeau, François [Auteur]
Behal, Hélène [Auteur]
Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Labreuche, Julien [Auteur]
Service de Biostatistiques [CHRU Lille]
Klein, Cédric [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Schurtz, Guillaume [Auteur]
Institut Coeur Poumon [CHU Lille]
Potelle, Charlotte [Auteur]
Coisne, Augustin [Auteur]
Lemesle, Gilles [Auteur]
Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U 1011 [RNMCD]
Alliance française pour les essais cliniques cardio-vasculaires - French Alliance for Cardiovascular Trials [FACT]
Institut Coeur Poumon [CHU Lille]
Lamblin, Nicolas [Auteur]
Institut Pasteur de Lille
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]
Klug, Didier [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Lacroix, Dominique [Auteur]
Institut Coeur Poumon [CHU Lille]

Journal title :

European Heart Journal: Acute Cardiovascular Care

Pages :

431-439

Publisher :

SAGE Publications

Publication date :

2022-05-04

ISSN :

2048-8726

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Abstract Aims For assessing predictors of early mortality following hospitalization for electrical storm (ES), only limited data are available. The purpose of this study was to assess the incidence and predictors of early ...
Show more >Abstract Aims For assessing predictors of early mortality following hospitalization for electrical storm (ES), only limited data are available. The purpose of this study was to assess the incidence and predictors of early mortality following hospitalization in the intensive care unit (ICU) for ES in a large retrospective study. Methods and results In this retrospective study, we included all patients who were hospitalized for ES from July 2015 to May 2020 in our tertiary centre. A total of 253 patients were included. The median age was 66 [56; 73], and 64% had ischemic cardiomyopathy. A total of 37% of patients presented hemodynamic instability requiring catecholamine at admission. A total of 17% of patients presented an acute reversible cause for ES. The one-year mortality was 34% (95% CI, 30–43%), mostly driven by heart failure (HF). The multivariable Cox's regression model identified age, left ventricular ejection fraction, right ventricle dysfunction, haemoglobin level as independent predictors of one-year mortality. The use of catecholamine at admission was identified as the only variable related to the initial management of ES associated with an increased 30-day mortality risk (HR: 7.95 (95%CI, 3.18–19.85). Conclusion In patients admitted for ES in ICU, the one-year mortality remains high and mostly driven by HF. The use of catecholamine at admission is associated with a seven-fold risk for mortality within 30 days. In such patients, the potential use of VT ablation can be questioned and a careful action plan regarding invasive HF-related therapy could be considered.Show less >

Language :

Anglais

Collections :

• Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (RNMCD) - U1011

Source :

Harvested from HAL

Submission date :

2023-11-10T03:30:07Z