Titre :

Neurophysiological recordings improve the accuracy of the evaluation of the outcome in perinatal hypoxic ischemic encephalopathy

Auteur(s) :

Delval, Arnaud [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Girard, B. [Auteur]
Lacan, L. [Auteur]
Chaton, L. [Auteur]
Flamein, F. [Auteur]
Storme, Laurent [Auteur]
METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694
Derambure, Philippe [Auteur]
Lille Neurosciences & Cognition - U 1172 [LilNCog]
Nguyen The Tich, Sylvie [Auteur]
Lamblin, M. D. [Auteur]
Betrouni, Nacim [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172

Titre de la revue :

European Journal of Paediatric Neurology

Nom court de la revue :

Eur J Paediatr Neurol

Numéro :

36

Pagination :

p. 51-56

Date de publication :

2022-01

ISSN :

1532-2130

Mot(s)-clé(s) en anglais :

Perinatal asphyxia
Hypoxic ischemic encephalopathy
Neonatal EEG
Evoked potentials

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Objectives Our objective was to evaluate the potential additional value of electroencephalogram (EEG) and evoked potentials in neonates with hypoxic-ischemic encephalopathy to predict their disability at 1 and 2 years ...
Lire la suite >Objectives Our objective was to evaluate the potential additional value of electroencephalogram (EEG) and evoked potentials in neonates with hypoxic-ischemic encephalopathy to predict their disability at 1 and 2 years old. Methods 30 full-term infants after perinatal asphyxia who underwent therapeutic hypothermia were evaluated at 1 year and 2 years for disability using International Classification of Functioning, Disability and Health classification. Scores for EEG, sensory evoked potentials and brainstem auditory evoked potentials were evaluated after withdrawal of therapeutic hypothermia that lasted 72 h. A regression approach was investigated to build models allowing to distinguish neonates according to their disability at 1 and 2 years. Two models were built, the first by considering the clinical data and EEG before and after therapeutic hypothermia and the second by incorporating evoked potentials recording. Results Adding EEG and evoked potentials data after rewarming improved dramatically the accuracy of the model considering outcome at 1 and 2 years. Interpretation We propose to record systematically EEG and evoked potentials following rewarming to predict the outcome of neonates with hypoxic ischemic encephalopathy. Combination of altered evoked potentials with no improvement of EEG after rewarming appeared to be a robust criterion for a poor outcome.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
CHU Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172
• METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694

Date de dépôt :

2023-11-15T05:22:55Z
2024-04-15T12:41:13Z