Titre :

Long-term follow-up of survivors of a first acute coronary syndrome: Results from the French MONICA registries from 2009 to 2017

Auteur(s) :

Gauthier, Victoria [Auteur]
Lafrance, Martin [Auteur]
Barthoulot, Maël [Auteur]
Rousselet, Louis [Auteur]
Montaye, Michèle [Auteur]
Ferrières, Jean [Auteur]
Service Cardiologie [CHU Toulouse]
Equipe Vieillissement (CERPOP)
Kai, Samantha Huo Yung [Auteur]
Equipe Vieillissement (CERPOP)
Service Epidémiologie clinique et santé publique [CHU Toulouse]
Biasch, Katia [Auteur]
Moitry, Marie [Auteur]
Amouyel, Philippe [Auteur]
Dallongeville, Jean [Auteur]
Meirhaeghe, Aline [Auteur]
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 [RID-AGE]

Titre de la revue :

International Journal of Cardiology

Pagination :

138-143

Éditeur :

Elsevier

Date de publication :

2023-05-01

ISSN :

0167-5273

Mot(s)-clé(s) en anglais :

Acute coronary syndrome
Registry
Morbidity
Mortality
Recurrence

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Aim: The objectives of the study were to characterize the long-term risk of first recurrence of acute coronarysyndrome (ACS) among survivors of an incident ACS, as a function of the STEMI/NSTEMI/UA diagnosis.Methods: Men ...
Lire la suite >Aim: The objectives of the study were to characterize the long-term risk of first recurrence of acute coronarysyndrome (ACS) among survivors of an incident ACS, as a function of the STEMI/NSTEMI/UA diagnosis.Methods: Men and women (aged 35–74) hospitalized between 2009 and 2016 for an incident ACS in the FrenchMONICA registries and still alive on discharge were followed-up until December 2017. Recurrent events weredefined as the first (non-fatal or fatal) ACS occurring after hospital discharge from the incident event.Results: The study comprised 15,739 incident ACSs with 63,777 patient-years of follow-up. The cumulativeprobability [95% confidence interval] of recurrent ACS was 6.7% [6.3–7.1%] at 1 year and 18.4% [17.4–19.5%]at 9 years. The cumulative probability of fatal recurrent ACS was 1.4% [1.2–1.5%] at 1 year and 4.3%[3.6–4.9%] at 9 years. The risk of recurrence did not depend on the type of the incident ACS after adjustment forconfounding factors. The most frequent forms of recurrence were NSTEMI and UA. The presence of a majorcomplication (OR = 1.59) and an impaired left ventricular ejection fraction (LVEF) (OR > 1.26) increased therisk of recurrence. The annual 1-year recurrence rates decreased from 7.4% in 2009 to 4.0% in 2016 (p < 0.001).Conclusion: The recurrence rate after an incident ACS remained high in France, and the risk of recurrence did notdepend on the etiology of the first event. Our results emphasize the importance of targeting patients with a major complication and/or an impaired LVEF who are at a higher risk of recurrence.Lire moins >

Langue :

Anglais

Comité de lecture :

Oui

Audience :

Internationale

Vulgarisation :

Non

Collections :

• Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) - U1167

Source :

Harvested from HAL