Title :

Is survival rate lower after breast cancer in deprived women according to disease stage?

Author(s) :

Delacote, Claire [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Delacour-Billon, Solenne [Auteur]
Réseau des registres français du cancer [FRANCIM]
Ayrault-Piault, Stéphanie [Auteur]
Réseau des registres français du cancer [FRANCIM]
Tagri, Anne-Delphine [Auteur]
Site de Recherche Intégrée sur le Cancer - Imaging and Longitudinal Investigations to Ameliorate Decision-making [SIRIC-ILIAD]
Rousseau, Gwenaëlle [Auteur]
Site de Recherche Intégrée sur le Cancer - Imaging and Longitudinal Investigations to Ameliorate Decision-making [SIRIC-ILIAD]
Vincent, Mélissa [Auteur]
Site de Recherche Intégrée sur le Cancer - Imaging and Longitudinal Investigations to Ameliorate Decision-making [SIRIC-ILIAD]
Amossé, Sophie [Auteur]
Site de Recherche Intégrée sur le Cancer - Imaging and Longitudinal Investigations to Ameliorate Decision-making [SIRIC-ILIAD]
Delpierre, Cyrille [Auteur]
Centre d'Epidémiologie et de Recherche en santé des POPulations [CERPOP]
Cowppli-Bony, Anne [Auteur]
Réseau des registres français du cancer [FRANCIM]
Centre d'Epidémiologie et de Recherche en santé des POPulations [CERPOP]
Molinié, Florence [Auteur]
Site de Recherche Intégrée sur le Cancer - Imaging and Longitudinal Investigations to Ameliorate Decision-making [SIRIC-ILIAD]

Journal title :

British Journal of Cancer

Abbreviated title :

Br J Cancer

Volume number :

128

Pages :

63–70

Publication date :

2022-11-05

ISSN :

1532-1827

English keyword(s) :

Breast cancer
Epidemiology

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Background Socioeconomic deprivation has been associated with lower breast cancer (BC) survival, but the influence of stage at diagnosis on this association merits further study. Our aim was to investigate this association ...
Show more >Background Socioeconomic deprivation has been associated with lower breast cancer (BC) survival, but the influence of stage at diagnosis on this association merits further study. Our aim was to investigate this association using the Loire-Atlantique/Vendee Cancer Registry (France). Methods Twelve-thousand seven-hundred thirty-eight women living in the area covered by the registry and diagnosed with invasive breast carcinoma between 2008 and 2015 were included in the study. They were censored at maximal 6 years. Deprivation was measured by the French European Deprivation Index. Excess hazard and net survival were estimated for deprivation level, stage and age at diagnosis using a flexible excess mortality hazard model. Results After adjustment by stage, women living in the most deprived areas had a borderline non-significant higher excess mortality hazard (+25% (95% CI: −3%; +62%)) compared to those living in the least deprived areas. Stage-adjusted 5-year net survival differed significantly between these two subgroups (respectively, 88.2% (95% CI:85.2%-90.5%) and 92.5% (95% CI:90.6%-93.9%)). Conclusion BC survival remained lower in deprived areas in France, despite universal access to cancer care. Intensification of prevention measures could help to reduce advanced BC, responsible for the majority of deaths from BC. A better understanding of remaining social disparities is crucial to implement specific interventions.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2024-01-12T00:09:44Z
2024-02-27T12:29:55Z
2024-02-28T07:46:53Z