Title :

Safety of dried fruits of <i>Synsepalum dulcificum</i> as a novel food pursuant to Regulation (EU) 2015/2283.

Author(s) :

Turck, Dominique [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Castenmiller, J. [Auteur]
European Food Safety Authority [EFSA]
De Henauw, S. [Auteur]
Hirsch-Ernst, K. I. [Auteur]
Kearney, J. [Auteur]
Maciuk, A. [Auteur]
Mangelsdorf, I. [Auteur]
Mcardle, H. J. [Auteur]
Naska, A. [Auteur]
Pelaez, C. [Auteur]
Pentieva, K. [Auteur]
Siani, A. [Auteur]
Thies, F. [Auteur]
Tsabouri, S. [Auteur]
Vinceti, M. [Auteur]
Cubadda, F. [Auteur]
Frenzel, T. [Auteur]
Heinonen, M. [Auteur]
Marchelli, R. [Auteur]
Neuhäuser-Berthold, M. [Auteur]
Poulsen, M. [Auteur]
Maradona, M. P. [Auteur]
Schlatter, J. R. [Auteur]
Van Loveren, H. [Auteur]
Matijević, L. [Auteur]
Knutsen, H. K. [Auteur]

Journal title :

EFSA Journal

Abbreviated title :

EFSA J

Volume number :

19

Pages :

e06600

Publication date :

2021-07-03

ISSN :

1831-4732

English keyword(s) :

food supplement
safety
novel food
Dried fruits of Synsepalum dulcificum

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods andFood Allergens (NDA) was asked to deliver an opinion on dried fruits ofSynsepalum dulcificumas anovel food (NF) pursuant to ...
Show more >Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods andFood Allergens (NDA) was asked to deliver an opinion on dried fruits ofSynsepalum dulcificumas anovel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is pitted and dried (by lyophilisation)fruits ofS. dulcificum. The NF contains the glycoprotein miraculin (≤2.5%) which causes sour andacidic foods to taste sweet. The fruits have a documented history of consumption in Africa andproducts thereof can be found in different markets worldwide. Information on the production processand the composition of the NF is sufficient and does not raise safety concerns. The applicant proposesto use the NF as or in food supplements for the adult population, excluding pregnant and lactatingwomen, at a maximum daily amount of 0.9 g. Taking into account these conditions of use, thePanel considers that the consumption of the NF is not nutritionally disadvantageous. The providedgenotoxicity studies do not raise concerns for genotoxicity of the NF. The Panel concludes that the onlydose tested in a 90-day oral toxicity study of 2,000 mg/kg body weight (bw) per day was notassociated with adverse effects. By applying an uncertainty factor of 200, the Panel concludes that theNF is safe at an intake level of 10 mg/kg bw per day, corresponding to a maximum daily intake of 0.7 g ofthe NF for the target population, rather than 0.9 g/day as proposed by the applicant.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2024-01-12T06:42:38Z
2024-02-28T12:25:47Z