Titre :

Prospective Evaluation of a Commercial Dengue NS1 Antigen Rapid Diagnostic Test in New Caledonia.

Auteur(s) :

Alidjinou, Enagnon Kazali [Auteur]
Laboratoire de virologie - ULR 3610
Tardieu, Sylvie [Auteur]
Vrenken, Isabelle [Auteur]
Hober, Didier [Auteur]
Laboratoire de virologie - ULR 3610
Gourinat, Ann-Claire [Auteur]
Centre hospitalier territorial Gaston-Bourret [Dumbea] [CHT]

Titre de la revue :

Microorganisms

Nom court de la revue :

Microorganisms

Numéro :

10

Pagination :

346

Date de publication :

2022-03-03

ISSN :

2076-2607

Mot(s)-clé(s) en anglais :

dengue virus
NS1 antigen
rapid diagnostic test
RT-PCR
evaluation

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Dengue virus infection is endemic in New Caledonia, with outbreaks occurring every year. We evaluated the Biosynex® Dengue NS1 antigen rapid diagnostic test (RDT) for the early diagnosis of dengue in patients attending a ...
Lire la suite >Dengue virus infection is endemic in New Caledonia, with outbreaks occurring every year. We evaluated the Biosynex® Dengue NS1 antigen rapid diagnostic test (RDT) for the early diagnosis of dengue in patients attending a local hospital in northern New Caledonia. Samples collected from patients suspected of dengue infection were tested with RDT at the local laboratory, and then sent to the reference laboratory for confirmation with real-time RT-PCR. A total of 472 samples were included during the study period. RT-PCR yielded a positive result in 154 samples (32.6%). The sensitivity and specificity of the NS1 antigen RDT were 79.9% and 96.2%, respectively. The performance of the RDT varied by the time of sampling and dengue virus serotype. In conclusion, Biosynex® Dengue NS1 antigen RDT showed a sensitivity and a specificity in the upper range usually reported for this type of test. Several factors can lead to a suboptimal sensitivity, and negative samples with suggestive clinical features should be retested with reference methods.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
CHU Lille

Collections :

• Laboratoire de virologie - ULR 3610

Date de dépôt :

2024-01-17T22:09:18Z
2024-02-09T07:43:10Z
2024-02-15T07:48:48Z