Titre :

Postoperative morbidity after iterative ileocolonic resection for crohn''s disease: should we be worried? a prospective multicentric cohort study of the getaid chirurgie

Auteur(s) :

Abdalla, Solafah [Auteur]
Brouquet, Antoine [Auteur]
Maggiori, Leon [Auteur]
Zerbib, Philippe [Auteur]
Denost, Quentin [Auteur]
Germain, Adeline [Auteur]
Cotte, Eddy [Auteur]
Beyer-Berjot, Laura [Auteur]
Munoz-Bongrand, Nicolas [Auteur]
Desfourneaux, Veronique [Auteur]
Rahili, Amine [Auteur]
Duffas, Jean-Pierre [Auteur]
Pautrat, Karine [Auteur]
Denet, Christine [Auteur]
Bridoux, Valerie [Auteur]
Meurette, Guillaume [Auteur]
Faucheron, Jean-Luc [Auteur]
Loriau, Jerome [Auteur]
Guillon, Francoise [Auteur]
Vicaut, Eric [Auteur]
Benoist, Stephane [Auteur]
Histoire Archéologie Littératures des Mondes Anciens (HALMA) - UMR 8164
Panis, Yves [Auteur]
Lefevre, Jeremie H. [Auteur]

Titre de la revue :

Journal of Crohn's & colitis

Nom court de la revue :

J Crohns Colitis

Date de publication :

2019-05-04

ISSN :

1876-4479

Mot(s)-clé(s) en anglais :

morbidity
ileo-colic resection
recurrent disease
Crohn's disease

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

OBJECTIVE: To compare perioperative characteristics and outcomes between primary ileocolonic resection [PICR] and iterative ileocolic resection [IICR] for Crohn's disease [CD]. METHODS: From 2013 to 2015, 567 patients ...
Lire la suite >OBJECTIVE: To compare perioperative characteristics and outcomes between primary ileocolonic resection [PICR] and iterative ileocolic resection [IICR] for Crohn's disease [CD]. METHODS: From 2013 to 2015, 567 patients undergoing ileocolonic resection were prospectively included in 19 centres of the GETAID chirurgie group. Perioperative characteristics and postoperative results of both groups [431 PICR, 136 IICR] were compared. Uni- and multivariate analyses of the risk factors of overall 30-day postoperative morbidity was carried out in the IICR group. RESULTS: IICR patients were less likely to be malnourished [27.2% vs 39.9%, p = 0.007], and had more stricturing forms [69.1% vs 54.3%, p = 0.002] and less perforating disease [19.9% vs 39.2%, p < 0.001]. Laparoscopy was less commonly used in IICR [45.6% vs 84.5%, p < 0.01] and was associated with increased conversion rates [27.4% vs 14.6%, p = 0.012]. Overall postoperative morbidity was 36.8% in the IICR group and 26.7% in the PICR group [p = 0.024]. There was no significant difference between IICR and PICR regarding septic intra-abdominal complications, anastomotic leakage [8.8% vs 8.4%] or temporary stoma requirement. IICR patients were more likely to present with non-infectious complications and ileus [11.8% vs 3.7%, p < 0.001]. Uni- and multivariate analyses did not identify specific risk factors of overall postoperative morbidity in the IICR group. CONCLUSIONS: Surgery for recurrent CD is associated with a slight increase of non-infectious morbidity [postoperative ileus] that mainly reflects the technical difficulties of these procedures. However, IICR remains a safe therapeutic option in patients with recurrent CD because severe morbidity including anastomotic complications is similar to patients undergoing primary resection. This article has an associated podcast which can be accessed at https://academic.oup.com/ecco-jcc/pages/podcast.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
CNRS
Inserm
Ministère de la Culture
Université de Lille

Collections :

• Histoire Archéologie Littératures des Mondes Anciens (HALMA) - UMR 8164
• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Date de dépôt :

2024-01-30T10:28:13Z