Differential gene expression profile of ...
Document type :
Article dans une revue scientifique: Article original
PMID :
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Title :
Differential gene expression profile of male and female copepods in response to cadmium exposure.
Author(s) :
Kadiene, Esther U [Auteur]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Ouddane, Baghdad [Auteur]
Laboratoire Avancé de Spectroscopie pour les Intéractions la Réactivité et l'Environnement (LASIRE) - UMR 8516
Gong, H. Y. [Auteur]
Kim, M. S. [Auteur]
Lee, J. S. [Auteur]
Pan, Yen-Ju [Auteur]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Hwang, J. S. [Auteur]
Souissi, Sami [Auteur]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Ouddane, Baghdad [Auteur]
Laboratoire Avancé de Spectroscopie pour les Intéractions la Réactivité et l'Environnement (LASIRE) - UMR 8516
Gong, H. Y. [Auteur]
Kim, M. S. [Auteur]
Lee, J. S. [Auteur]
Pan, Yen-Ju [Auteur]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Hwang, J. S. [Auteur]
Souissi, Sami [Auteur]
Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 [LOG]
Journal title :
Ecotoxicology and Environmental Safety
Abbreviated title :
Ecotoxicol. Environ. Saf.
Volume number :
204
Pages :
111048
Publication date :
2020-08-09
ISSN :
1090-2414
English keyword(s) :
Cadmium
Toxicity
Pseudodiaptomus annandalei
Sex
Transcriptome
Physiology
Toxicity
Pseudodiaptomus annandalei
Sex
Transcriptome
Physiology
HAL domain(s) :
Planète et Univers [physics]/Sciences de la Terre/Géochimie
English abstract : [en]
In this study, the whole transcriptome and sex-specific differential gene expression of the copepod Pseudodiaptomus annandalei exposed to cadmium (Cd) were investigated. P. annandalei were exposed to 40 μg/L Cd from the ...
Show more >In this study, the whole transcriptome and sex-specific differential gene expression of the copepod Pseudodiaptomus annandalei exposed to cadmium (Cd) were investigated. P. annandalei were exposed to 40 μg/L Cd from the naupliar stage to male and female adults. High-throughput transcriptome sequencing (RNA-seq) was performed with copepod samples using an Illumina Hiseq™ 2000 platform. TransDecoder analysis found 32,625 putative open reading frame contigs. At p-values of <0.001, a total of 4756 differentially expressed genes (DEGs) (2216 up-regulated and 2540 down-regulated genes) were found in male copepods. Whereas a total of 2879 DEGs (2007 up-regulated and 872 down-regulated genes) were found in female copepods. A few selected cellular stress response genes, involved in xenobiotic metabolism, energy metabolism, growth, and development as a result of Cd exposure in the copepods were discussed. The study showed that most of these processes were changed in a sex-specific manner, accounting for the different sensitivities of male and female copepods. Results suggest and reinforce that sex is an important factor to be considered in ecotoxicogenomics.Show less >
Show more >In this study, the whole transcriptome and sex-specific differential gene expression of the copepod Pseudodiaptomus annandalei exposed to cadmium (Cd) were investigated. P. annandalei were exposed to 40 μg/L Cd from the naupliar stage to male and female adults. High-throughput transcriptome sequencing (RNA-seq) was performed with copepod samples using an Illumina Hiseq™ 2000 platform. TransDecoder analysis found 32,625 putative open reading frame contigs. At p-values of <0.001, a total of 4756 differentially expressed genes (DEGs) (2216 up-regulated and 2540 down-regulated genes) were found in male copepods. Whereas a total of 2879 DEGs (2007 up-regulated and 872 down-regulated genes) were found in female copepods. A few selected cellular stress response genes, involved in xenobiotic metabolism, energy metabolism, growth, and development as a result of Cd exposure in the copepods were discussed. The study showed that most of these processes were changed in a sex-specific manner, accounting for the different sensitivities of male and female copepods. Results suggest and reinforce that sex is an important factor to be considered in ecotoxicogenomics.Show less >
Language :
Anglais
Peer reviewed article :
Oui
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Université de Lille
CNRS
CNRS
Collections :
Submission date :
2024-02-28T22:54:57Z
2024-03-12T11:48:10Z
2024-03-12T11:48:10Z
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