Influence of physical fitness on antioxidant ...
Document type :
Article dans une revue scientifique
DOI :
PMID :
Permalink :
Title :
Influence of physical fitness on antioxidant activity and malondialdehyde level in healthy older adults
Author(s) :
Bouzid, Mohamed Amine [Auteur]
Activité Physique, Muscle, Santé [EA4488]
Hammouda, Omar [Auteur]
Université Paris Nanterre [UPN]
Matran, Regis [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Robin, Sophie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Fabre, Claudine [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Activité Physique, Muscle, Santé [EA4488]
Hammouda, Omar [Auteur]
Université Paris Nanterre [UPN]
Matran, Regis [Auteur]
IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Robin, Sophie [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Fabre, Claudine [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Journal title :
Applied Physiology, Nutrition, and Metabolism
Abbreviated title :
Appl. Physiol. Nutr. Metab.
Volume number :
40
Pages :
582-589
Publisher :
Canadian Science Publishing
Publication date :
2015-06-06
ISSN :
1715-5312
English keyword(s) :
aging
physical activity
fitness
antioxidant defense
exercise
lipid peroxidation
physical activity
fitness
antioxidant defense
exercise
lipid peroxidation
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
The aim of this study was to investigate how physical fitness level could affect antioxidant activity and malondialdehyde (MDA) level at rest and in response to exhaustive exercise in healthy older adults. Fifty older ...
Show more >The aim of this study was to investigate how physical fitness level could affect antioxidant activity and malondialdehyde (MDA) level at rest and in response to exhaustive exercise in healthy older adults. Fifty older adults (average age: 66.1 ± 3.8 years) were divided according to their physical fitness level into an unfit group (UG) (n = 15), a low fitness level group (LFG) (n = 18), and a high fitness level group (HFG) (n = 17). Fitness status was classified based on answers to a questionnaire about physical activity in the previous 12 months. Before and after an incremental cycle ergometer test to exhaustion, the following markers were assessed: superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione reductase, ascorbic acid, α-tocopherol, and MDA. At rest, SOD, GPX, and α-tocopherol activities were higher in the HFG (p < 0.05), whereas MDA level was lower in the LFG in comparison with the 2 other groups (p < 0.05). During the postexercise period, antioxidant activity increased only in the LFG and the HFG (GPX, SOD, and α-tocopherol). MDA level increased in all groups after the exercise (p < 0.05). In addition, MDA level was higher during the recovery period in the HFG as compared with the others groups. This study concluded that both low and high physical fitness levels help maintain better antioxidant defenses in older adults. However, a higher physical fitness level, rather than a lower physical fitness level, could increase lipid peroxidation.Show less >
Show more >The aim of this study was to investigate how physical fitness level could affect antioxidant activity and malondialdehyde (MDA) level at rest and in response to exhaustive exercise in healthy older adults. Fifty older adults (average age: 66.1 ± 3.8 years) were divided according to their physical fitness level into an unfit group (UG) (n = 15), a low fitness level group (LFG) (n = 18), and a high fitness level group (HFG) (n = 17). Fitness status was classified based on answers to a questionnaire about physical activity in the previous 12 months. Before and after an incremental cycle ergometer test to exhaustion, the following markers were assessed: superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione reductase, ascorbic acid, α-tocopherol, and MDA. At rest, SOD, GPX, and α-tocopherol activities were higher in the HFG (p < 0.05), whereas MDA level was lower in the LFG in comparison with the 2 other groups (p < 0.05). During the postexercise period, antioxidant activity increased only in the LFG and the HFG (GPX, SOD, and α-tocopherol). MDA level increased in all groups after the exercise (p < 0.05). In addition, MDA level was higher during the recovery period in the HFG as compared with the others groups. This study concluded that both low and high physical fitness levels help maintain better antioxidant defenses in older adults. However, a higher physical fitness level, rather than a lower physical fitness level, could increase lipid peroxidation.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
Univ. Littoral Côte d’Opale
Univ. Artois
Université de Lille
Institut Pasteur de Lille
Univ. Littoral Côte d’Opale
Univ. Artois
Université de Lille
Institut Pasteur de Lille
Collections :
Research team(s) :
Activité Physique, Muscle, Santé (APMS)
Submission date :
2019-09-24T07:27:57Z
2022-04-27T10:17:57Z
2024-02-07T06:56:15Z
2022-04-27T10:17:57Z
2024-02-07T06:56:15Z
Files
- Bouzid et al.pdf
- Version éditeur
- Restricted access
- Access the document