Long-term cognitive outcomes after ...
Type de document :
Article dans une revue scientifique: Article original
DOI :
PMID :
URL permanente :
Titre :
Long-term cognitive outcomes after decompressive hemicraniectomy for right-hemisphere large middle cerebral artery ischemic stroke
Auteur(s) :
Scopelliti, Giuseppe [Auteur]
Lille Neurosciences & Cognition - U 1172 [LilNCog]
Henon, Hilde [Auteur]
Lille Neurosciences & Cognition - U 1172 [LilNCog]
Labreuche, Julien [Auteur]
Service de Biostatistiques [CHRU Lille]
Kuchcinski, Gregory [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Aboukais, Rabih [Auteur]
Département de Neurochirurgie[Lille]
Cordonnier, Charlotte [Auteur]
Lille Neurosciences & Cognition - U 1172 [LilNCog]
Casolla, Barbara [Auteur]
Université Côte d'Azur [UniCA]
Lille Neurosciences & Cognition - U 1172 [LilNCog]
Henon, Hilde [Auteur]

Lille Neurosciences & Cognition - U 1172 [LilNCog]
Labreuche, Julien [Auteur]
Service de Biostatistiques [CHRU Lille]
Kuchcinski, Gregory [Auteur]

Lille Neurosciences & Cognition (LilNCog) - U 1172
Aboukais, Rabih [Auteur]
Département de Neurochirurgie[Lille]
Cordonnier, Charlotte [Auteur]

Lille Neurosciences & Cognition - U 1172 [LilNCog]
Casolla, Barbara [Auteur]
Université Côte d'Azur [UniCA]
Titre de la revue :
European Journal of Neurology
Nom court de la revue :
Eur. J. Neurol.
Numéro :
32
Pagination :
e16492
Éditeur :
Wiley Online Library
Date de publication :
2024-11-18
ISSN :
1351-5101
Mot(s)-clé(s) en anglais :
cognitive impairment
decompressive hemicraniectomy
ischemic stroke
decompressive hemicraniectomy
ischemic stroke
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Background and Purpose
Decompressive hemicraniectomy (DH) improves survival and functional outcome in large middle cerebral artery (MCA) infarcts. However, long-term cognitive outcomes after DH remain underexplored. In a ...
Lire la suite >Background and Purpose Decompressive hemicraniectomy (DH) improves survival and functional outcome in large middle cerebral artery (MCA) infarcts. However, long-term cognitive outcomes after DH remain underexplored. In a cohort of patients with large right-hemisphere MCA infarction undergoing DH, we assessed the rates of long-term cognitive impairment over 3-year follow-up. Methods We prospectively evaluated consecutive patients included in the Lille Decompressive Surgery Database (May 2005–April 2022) undergoing DH according to existing guidelines for large hemisphere MCA infarction. We included patients with right-sided stroke and screened with the Mini-Mental State Examination (MMSE) in at least one of the prespecified follow-ups (3-month, 1-year, 3-year). Cognitive impairment was defined as an MMSE score < 24. We included only right-hemisphere strokes to avoid testing biases related to severe aphasia. We compared clinical and neuroimaging data in patients with and without cognitive impairment. Results Three hundred four patients underwent DH during the study period. Among 3-month survivors, 95 had a right-hemisphere stroke and underwent at least one cognitive screening (median age = 51 years, 56.8% men). Forty-four patients (46.3%) exhibited cognitive impairment at least once during the 3-year follow-up. Baseline characteristics did not significantly differ between patients with and without cognitive impairment. Regarding long-term temporal trends, cognitive impairment was observed in 23 of 76 (30.3%), 25 of 80 (31.3%), and 19 of 66 (28.8%) patients at 3-month, 1-year, and 3-year follow-up, respectively, and it was associated with higher rates of functional disability (all p < 0.05). Conclusions The persistently high rates of cognitive impairment after DH highlight the importance of cognitive monitoring to improve the long-term management of survivors.Lire moins >
Lire la suite >Background and Purpose Decompressive hemicraniectomy (DH) improves survival and functional outcome in large middle cerebral artery (MCA) infarcts. However, long-term cognitive outcomes after DH remain underexplored. In a cohort of patients with large right-hemisphere MCA infarction undergoing DH, we assessed the rates of long-term cognitive impairment over 3-year follow-up. Methods We prospectively evaluated consecutive patients included in the Lille Decompressive Surgery Database (May 2005–April 2022) undergoing DH according to existing guidelines for large hemisphere MCA infarction. We included patients with right-sided stroke and screened with the Mini-Mental State Examination (MMSE) in at least one of the prespecified follow-ups (3-month, 1-year, 3-year). Cognitive impairment was defined as an MMSE score < 24. We included only right-hemisphere strokes to avoid testing biases related to severe aphasia. We compared clinical and neuroimaging data in patients with and without cognitive impairment. Results Three hundred four patients underwent DH during the study period. Among 3-month survivors, 95 had a right-hemisphere stroke and underwent at least one cognitive screening (median age = 51 years, 56.8% men). Forty-four patients (46.3%) exhibited cognitive impairment at least once during the 3-year follow-up. Baseline characteristics did not significantly differ between patients with and without cognitive impairment. Regarding long-term temporal trends, cognitive impairment was observed in 23 of 76 (30.3%), 25 of 80 (31.3%), and 19 of 66 (28.8%) patients at 3-month, 1-year, and 3-year follow-up, respectively, and it was associated with higher rates of functional disability (all p < 0.05). Conclusions The persistently high rates of cognitive impairment after DH highlight the importance of cognitive monitoring to improve the long-term management of survivors.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
Inserm
CHU Lille
Inserm
CHU Lille
Collections :
Date de dépôt :
2025-01-31T22:02:45Z
2025-02-26T09:54:20Z
2025-02-26T09:54:20Z
Fichiers
- Euro J of Neurology - 2024 - Scopelliti - Long‐term cognitive outcomes after decompressive hemicraniectomy for.pdf
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