Evaluation of single-extraction methods ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Evaluation of single-extraction methods to estimate the oral bioaccessibility of metal(loid)s in soils
Auteur(s) :
Pelfrene, Aurélie [Auteur correspondant]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Sahmer, Karin [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Waterlot, Christophe [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Glorennec, Philippe [Auteur]
Institut de recherche en santé, environnement et travail [Irset]
Département Santé Environnement Travail et Génie Sanitaire [DSETGS]
Douay, Francis [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Le Bot, Barbara [Auteur]
Laboratoire d'étude et de recherche en environnement et santé [LERES]
Institut de recherche en santé, environnement et travail [Irset]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Sahmer, Karin [Auteur]

Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Waterlot, Christophe [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Glorennec, Philippe [Auteur]
Institut de recherche en santé, environnement et travail [Irset]
Département Santé Environnement Travail et Génie Sanitaire [DSETGS]
Douay, Francis [Auteur]
Laboratoire de Génie Civil et Géo-Environnement (LGCgE) - ULR 4515 [LGCgE]
Le Bot, Barbara [Auteur]
Laboratoire d'étude et de recherche en environnement et santé [LERES]
Institut de recherche en santé, environnement et travail [Irset]
Titre de la revue :
Science of the Total Environment
Pagination :
138553
Éditeur :
Elsevier
Date de publication :
2020-04
ISSN :
0048-9697
Mot(s)-clé(s) en anglais :
Soil pollution
Human exposure
Single-extraction method
Metalloid
Metal
Human exposure
Single-extraction method
Metalloid
Metal
Discipline(s) HAL :
Sciences du Vivant [q-bio]/Santé publique et épidémiologie
Résumé en anglais : [en]
Incidental ingestion of polluted soil particles exposes the population to toxic metal(loid)s. To refine the methods of exposure and risk assessment, it is relevant to use bioaccessible concentrations of metal(loid)s ...
Lire la suite >Incidental ingestion of polluted soil particles exposes the population to toxic metal(loid)s. To refine the methods of exposure and risk assessment, it is relevant to use bioaccessible concentrations of metal(loid)s determined via in vitro digestion methods. However, some validated methods are complex and costly, involving high technical skills and numerous reagents. The objective of the present study was to evaluate the suitability of four simple chemical extractions to mimic the bioaccessible fraction of As, Cd, and Pb in the gastric (G) and gastrointestinal (GI) phases obtained using the validated UBM (unified bioaccessibility method) test. Acetic acid (0.11 M), citric acid (0.11 M), EDTA (0.16 M), and hydrochloric acid (HCl, 0.65%) were separately tested in 201 soil samples with a wide range of physicochemical parameters and metal(loid)s concentrations. Significant linear relationships were observed with HCl, EDTA, and to a lesser extent with citric acid. For the cheaper HCl method, correlations with the UBM ranged from 0.91 to 0.99 for the G phase and from 0.72 to 0.97 for the GI phase. This test can be used at least as a first-tier screening to assess the oral bioaccessibility of As, Cd, and Pb.Lire moins >
Lire la suite >Incidental ingestion of polluted soil particles exposes the population to toxic metal(loid)s. To refine the methods of exposure and risk assessment, it is relevant to use bioaccessible concentrations of metal(loid)s determined via in vitro digestion methods. However, some validated methods are complex and costly, involving high technical skills and numerous reagents. The objective of the present study was to evaluate the suitability of four simple chemical extractions to mimic the bioaccessible fraction of As, Cd, and Pb in the gastric (G) and gastrointestinal (GI) phases obtained using the validated UBM (unified bioaccessibility method) test. Acetic acid (0.11 M), citric acid (0.11 M), EDTA (0.16 M), and hydrochloric acid (HCl, 0.65%) were separately tested in 201 soil samples with a wide range of physicochemical parameters and metal(loid)s concentrations. Significant linear relationships were observed with HCl, EDTA, and to a lesser extent with citric acid. For the cheaper HCl method, correlations with the UBM ranged from 0.91 to 0.99 for the G phase and from 0.72 to 0.97 for the GI phase. This test can be used at least as a first-tier screening to assess the oral bioaccessibility of As, Cd, and Pb.Lire moins >
Langue :
Anglais
Comité de lecture :
Oui
Audience :
Internationale
Vulgarisation :
Non
Source :
Date de dépôt :
2025-02-26T12:51:25Z
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