Titre :

High‐Resolution Manometry With Solid Provocative Test in Patients With Mid‐Thoracic and Epiphrenic Esophageal Diverticula

Auteur(s) :

Baravian, Loris [Auteur]
Hôpital Claude Huriez [Lille]
Melchior, Chloé [Auteur]
Centre d'Investigation Clinique [CHU Rouen] [CIC Rouen]
Service d'Hépato-Gastroentérologie [CHU Rouen]
Université de Rouen Normandie [UNIROUEN]
Institute for Research and Innovation in Biomedicine [IRIB]
Nutrition, Inflammation et axe Microbiote-Intestin-Cerveau [ADEN]
Hambli, Sofia [Auteur]
Hôpital Claude Huriez [Lille]
Branche, Julien [Auteur]
Hôpital Claude Huriez [Lille]
Gérard, Romain [Auteur]
Hôpital Claude Huriez [Lille]
Wuestenberghs, Fabien [Auteur]
Hôpital Avicenne [AP-HP]
Centre d'Investigation Clinique [CHU Rouen] [CIC Rouen]
Service d'Hépato-Gastroentérologie [CHU Rouen]
Université de Rouen Normandie [UNIROUEN]
Institute for Research and Innovation in Biomedicine [IRIB]
Nutrition, Inflammation et axe Microbiote-Intestin-Cerveau [ADEN]
Piessen, Guillaume [Auteur]
Hôpital Claude Huriez [Lille]
Hétérogénéité, Plasticité et Résistance aux Thérapies des Cancers = Cancer Heterogeneity, Plasticity and Resistance to Therapies - UMR 9020 - U 1277 [CANTHER]
Gourcerol, Guillaume [Auteur]
Centre d'Investigation Clinique [CHU Rouen] [CIC Rouen]
Service d'Hépato-Gastroentérologie [CHU Rouen]
Université de Rouen Normandie [UNIROUEN]
Institute for Research and Innovation in Biomedicine [IRIB]
Nutrition, Inflammation et axe Microbiote-Intestin-Cerveau [ADEN]
Wils, Pauline [Auteur]
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Hôpital Claude Huriez [Lille]

Titre de la revue :

Neurogastroenterology & Motility

Éditeur :

Wiley

Date de publication :

2025-02-17

ISSN :

1350-1925

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

ABSTRACT Background The number of studies exploring esophageal motility disorders using high‐resolution manometry (HRM) in patients with esophageal diverticula (ED) is limited. The goal of this study was to describe motility ...
Lire la suite >ABSTRACT Background The number of studies exploring esophageal motility disorders using high‐resolution manometry (HRM) in patients with esophageal diverticula (ED) is limited. The goal of this study was to describe motility disorders using HRM in patients with ED and assess the added value of provocative testing in these patients. Methods Patients with ED who underwent HRM between 2010 and 2022 were retrospectively included. HRM findings were compared based on single water swallows (SWS), and provocative testing with solid food swallows in the upright seated position, using both ManoView and Medical Measurement Systems software. We also calculated median pressure slopes during the compartmentalization phase. Key Results Sixteen of the 39 included patients had mid‐ED and 23 had lower ED. Twenty (51.3%) patients had motility disorders based on SWS, including 7 (18%) with achalasia and 3 (7.7%) with esophagogastric junction obstruction. No significant differences in esophageal motility disorders were observed in relation to the location of the ED. Solid food swallows were performed in 29 (74%) patients leading to a change in the HRM diagnosis in 7 (24.1%), all of whom showed elevated IRP. Median pressure slopes during the compartmentalization phase ( n = 30) were elevated in patients both with and without motility disorders. Conclusion and Inferences Half of the patients with mid‐ or lower ED had motility disorders on HRM. Adding solid food swallows during HRM in patients with ED improves the manometric diagnosis. Results suggest abnormal distensibility in these patients, indicated by elevated pressure slope, regardless of the presence of associated motility disorders.Lire moins >

Langue :

Anglais

Comité de lecture :

Oui

Audience :

Internationale

Vulgarisation :

Non

Collections :

• Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277

Source :

Harvested from HAL

Date de dépôt :

2025-03-06T04:28:04Z