Titre :

Risk factors of postictal generalized eeg suppression in generalized convulsive seizures

Auteur(s) :

Alexandre, Veriano [Auteur]
Mercedes, Blanca [Auteur]
Valton, Luc [Auteur]
Maillard, Louis Georges [Auteur]
Bartolomei, Fabrice [Auteur]
Szurhaj, William [Auteur]
Troubles cognitifs dégénératifs et vasculaires - U1171
Troubles cognitifs dégénératifs et vasculaires - U 1171 - EA 1046 [TCDV]
Hirsch, Edouard [Auteur]
Marchal, Cecile [Auteur]
Chassoux, Francine [Auteur]
Petit, Jerome [Auteur]
Crespel, Arielle [Auteur]
Nica, Anca [Auteur]
Navarro, Vincent [Auteur]
Kahane, Philippe [Auteur]
De Toffol, Bertrand [Auteur]
Thomas, Pierre [Auteur]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab]
Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193
Rosenberg, Sarah-Dominique [Auteur]
Denuelle, Marie [Auteur]
Jonas, Jacques [Auteur]
Ryvlin, Philippe [Auteur]
Rheims, Sylvain [Auteur]

Titre de la revue :

Neurology

Nom court de la revue :

Neurology

Numéro :

85

Pagination :

1598-1603

Date de publication :

2015-11-03

ISSN :

0028-3878

Mot(s)-clé(s) en anglais :

Mesh:Early Medical Intervention
Mesh:Cohort Studies
Mesh:Brain Waves/physiology*
Mesh:Adult
Mesh:Prospective Studies
Mesh:Risk Factors
Mesh:Seizures/classification*
Mesh:Seizures/physiopathology
Mesh:Seizures/therapy
Mesh:Video Recording
Mesh:Odds Ratio
Mesh:Male
Mesh:Oxygen Inhalation Therapy/statistics & numerical data
Mesh:Humans
Mesh:Female
Mesh:Epilepsy
Mesh:Generalized/therapy
Mesh:Epilepsy
Mesh:Generalized/physiopathology
Mesh:Epilepsy
Mesh:Generalized/classification*
Mesh:Electroencephalography

Discipline(s) HAL :

Sciences du Vivant [q-bio]
Sciences cognitives

Résumé en anglais : [en]

OBJECTIVE: To identify the clinical determinants of occurrence of postictal generalized EEG suppression (PGES) after generalized convulsive seizures (GCS). METHODS: We reviewed the video-EEG recordings of 417 patients ...
Lire la suite >OBJECTIVE: To identify the clinical determinants of occurrence of postictal generalized EEG suppression (PGES) after generalized convulsive seizures (GCS). METHODS: We reviewed the video-EEG recordings of 417 patients included in the REPO2MSE study, a multicenter prospective cohort study of patients with drug-resistant focal epilepsy. According to ictal semiology, we classified GCS into 3 types: tonic-clonic GCS with bilateral and symmetric tonic arm extension (type 1), clonic GCS without tonic arm extension or flexion (type 2), and GCS with unilateral or asymmetric tonic arm extension or flexion (type 3). Association between PGES and person-specific or seizure-specific variables was analyzed after correction for individual effects and the varying number of seizures. RESULTS: A total of 99 GCS in 69 patients were included. Occurrence of PGES was independently associated with GCS type (p < 0.001) and lack of early administration of oxygen (p < 0.001). Odds ratio (OR) for GCS type 1 in comparison with GCS type 2 was 66.0 (95% confidence interval [CI 5.4-801.6]). In GCS type 1, risk of PGES was significantly increased when the seizure occurred during sleep (OR 5.0, 95% CI 1.2-20.9) and when oxygen was not administered early (OR 13.4, 95% CI 3.2-55.9). CONCLUSIONS: The risk of PGES dramatically varied as a function of GCS semiologic characteristics. Whatever the type of GCS, occurrence of PGES was prevented by early administration of oxygen.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
CNRS
Inserm
Université de Lille

Collections :

• Lille Neurosciences & Cognition (LilNCog) - U 1172

Équipe(s) de recherche :

Troubles cognitifs dégénératifs et vasculaires

Date de dépôt :

2019-11-27T14:29:57Z
2020-04-10T12:24:22Z