Biological based Biosensor’s Inception
Type de document :
Article dans une revue scientifique
URL permanente :
Titre :
Biological based Biosensor’s Inception
Auteur(s) :
Spriet, Corentin [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 [UGSF]
Kasprowicz, Angelina [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 [UGSF]
Bodart, Jean-Francois [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 [UGSF]
Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 [UGSF]
Kasprowicz, Angelina [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 [UGSF]
Bodart, Jean-Francois [Auteur]
Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 [UGSF]
Titre de la revue :
Journal of Biosensors, Biomarkers and Diagnostics
Numéro :
1
Pagination :
1-2
Date de publication :
2016-08-05
Discipline(s) HAL :
Chimie/Chimie théorique et/ou physique
Résumé en anglais : [en]
As an incipit, one has to define the term biosensor. The term has been enclosing several views and concepts, which we will not review here. Nevertheless, biological based biosensors can be common only defined as biological ...
Lire la suite >As an incipit, one has to define the term biosensor. The term has been enclosing several views and concepts, which we will not review here. Nevertheless, biological based biosensors can be common only defined as biological items, whose properties modifications upon environmental modifications can be measured. Herein this opinion article we will refer only to biosensors as the biological based ones, which cover [1] molecules : among the best characterized biosensors are the FRET (Förster Resonance Energy Transfer)-based, genetically encoded Kinase Activity Reporter (KAR) [1,2], (2) cells : CBB (Cells Based Biosensors; [3] and (3) organisms, like Xenopus embryos, whose development is sensitive to external factors (FETAX), Frog Embryo Teratogenesis Assay Xenopus [4] (Figure 1A). The untangling of complex signalling network is imperative both for understanding cells and organisms physiological and pathological contexts, and for isolating the ideal property modifications to measure that will reflect, for example, the deregulation of these networks. These modifications are the one seeked for biosensors design or choice. Then, biosensors become mandatory for deciphering and characterizing molecular signatures associated with pathologies. The latter aspect is naturally tightly linked to prognosis and diagnosis.Lire moins >
Lire la suite >As an incipit, one has to define the term biosensor. The term has been enclosing several views and concepts, which we will not review here. Nevertheless, biological based biosensors can be common only defined as biological items, whose properties modifications upon environmental modifications can be measured. Herein this opinion article we will refer only to biosensors as the biological based ones, which cover [1] molecules : among the best characterized biosensors are the FRET (Förster Resonance Energy Transfer)-based, genetically encoded Kinase Activity Reporter (KAR) [1,2], (2) cells : CBB (Cells Based Biosensors; [3] and (3) organisms, like Xenopus embryos, whose development is sensitive to external factors (FETAX), Frog Embryo Teratogenesis Assay Xenopus [4] (Figure 1A). The untangling of complex signalling network is imperative both for understanding cells and organisms physiological and pathological contexts, and for isolating the ideal property modifications to measure that will reflect, for example, the deregulation of these networks. These modifications are the one seeked for biosensors design or choice. Then, biosensors become mandatory for deciphering and characterizing molecular signatures associated with pathologies. The latter aspect is naturally tightly linked to prognosis and diagnosis.Lire moins >
Langue :
Anglais
Audience :
Non spécifiée
Établissement(s) :
CNRS
Université de Lille
Université de Lille
Équipe(s) de recherche :
Régulation des signaux de division
Date de dépôt :
2020-02-12T15:44:33Z
2021-03-05T08:08:10Z
2021-03-05T08:09:21Z
2021-03-05T08:10:50Z
2021-03-05T08:08:10Z
2021-03-05T08:09:21Z
2021-03-05T08:10:50Z
Fichiers
- biosensors-biomarkers-diagnostics03.pdf
- Version éditeur
- Accès libre
- Accéder au document