Impact of relative change in temperature and atmospheric pressure on acute aortic syndrome occurrence in france

Guimbretiere, Guillaume; Nusinovici, Simon; Monnot, Antoine; Sobocinski, Jonathan; Senage, Thomas; Delsart, Pascal; Gourraud, Pierre-Antoine; Maurel, Blandine

Type de document :

Article dans une revue scientifique: Article original

DOI :

10.1038/s41598-019-56841-w

PMID :

31919377

URL permanente :

http://hdl.handle.net/20.500.12210/36968

Titre :

Impact of relative change in temperature and atmospheric pressure on acute aortic syndrome occurrence in france

Auteur(s) :

Guimbretiere, Guillaume [Auteur]
Nusinovici, Simon [Auteur]
Monnot, Antoine [Auteur]
Sobocinski, Jonathan [Auteur]

Senage, Thomas [Auteur]
Delsart, Pascal [Auteur]
Gourraud, Pierre-Antoine [Auteur]
Maurel, Blandine [Auteur]

Titre de la revue :

Scientific Reports

Nom court de la revue :

Sci Rep

Numéro :

Pagination :

Date de publication :

2020-01-09

ISSN :

2045-2322

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Acute aortic syndromes (AAS) have been related to significant circadian and seasonal conditions. We used time series analyses to study the impact of meteorological variations on AAS occurrence. We retrospectively assessed ...
Lire la suite >Acute aortic syndromes (AAS) have been related to significant circadian and seasonal conditions. We used time series analyses to study the impact of meteorological variations on AAS occurrence. We retrospectively assessed 140 patients presenting with AAS over a 6-year period in a French university hospital. Average daily temperature (T) and atmospheric pressure (AP) at the location of the event were collected within the previous 10 days, and their association with AAS investigated with generalized additive models. A decrease in temperature of more than 5 °C within the previous seven days was significantly associated with an increased risk of AAS occurrence (OR equal to 1.86 [1.06; 3.44]). Subgroup analysis revealed that the risk was only significant among normotensive individuals (n = 41) free from blood pressure lowering medication (OR equal to 2.3 [1.05; 5.37]), but not among hypertensive individuals under blood pressure lowering medication despite a larger patient number (n = 99). Similarly, only among the subgroup of normotensive individuals a decrease of AP between 2 and 4 kPa within the previous 3 days was associated with an increased risk of AAS (OR equal to 2.93 [1.1; 8.15]) and an increased between 2 and 4 kPa was associated with a decreased risk (OR equal to 0.59 [0.36; 1.00]). Variations of meteorological conditions (temperature and AP) within the previous week seem to have effects on triggering AAS especially among the population free from blood pressure lowering medication.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Inserm
Université de Lille

Collections :

Advanced Drug Delivery Systems (ADDS) - U1008

Date de dépôt :

2021-01-20T15:58:58Z

Numéro de version	Lien	Date de modification
2	20.500.12210/36968	2024-02-15T10:39:33Z
1	20.500.12210/36968.1*	2021-01-20T15:58:58Z

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Impact of relative change in temperature ...

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CSV

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RIS