Title :

Mediation role of cardiorespiratory fitness on the association between fatness and cardiometabolic risk in European adolescents: The HELENA study.

Author(s) :

Cristi-Montero, Carlos [Auteur]
Pontificia Universidad Católica de Valparaíso [PUCV]
Courel-Ibáñez, Javier [Auteur]
Universidad de Murcia
Ortega, Francisco B [Auteur]
Universidad de Granada = University of Granada [UGR]
Castro-Piñero, Jose [Auteur]

Santaliestra-Pasias, Alba [Auteur]
Universidad de Zaragoza = University of Zaragoza [Saragossa University] = Université de Saragosse
Polito, Angela [Auteur]
Consiglio per la Ricerca in Agricoltura e l’analisi dell’economia agraria = Council for Agricultural Research and Economics [CREA]
Vanhelst, Jeremy [Auteur]
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Marcos, Ascensión [Auteur]
Consejo Superior de Investigaciones Cientificas [España] = Spanish National Research Council [Spain] [CSIC]
Moreno, Luis M [Auteur]
Universidad de Zaragoza = University of Zaragoza [Saragossa University] = Université de Saragosse
Ruiz, Jonatan R [Auteur]

Journal title :

Journal of sport and health science

Abbreviated title :

J Sport Health Sci

Volume number :

10

Pages :

360-367

Publication date :

2021-05-01

ISSN :

2213-2961

English keyword(s) :

Cardiovascular disease
Children
Fat mass
Fitness
Health
Physical activity

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

This study was aimed to analyze the mediation role of cardiorespiratory fitness (CRF) on the association between fatness and cardiometabolic risk scores (CMRs) in European adolescents. A cross-sectional study was conducted ...
Show more >This study was aimed to analyze the mediation role of cardiorespiratory fitness (CRF) on the association between fatness and cardiometabolic risk scores (CMRs) in European adolescents. A cross-sectional study was conducted in adolescents (n = 525; 46% boys; 14.1 ± 1.1 years old, mean ± SD) from 10 European cities involved in the Healthy Lifestyle in Europe by Nutrition in Adolescence study. CRF was measured by means of the shuttle run test, while fatness measures included body mass index (BMI), waist to height ratio, and fat mass index estimated from skinfold thicknesses. A clustered CMRs was computed by summing the standardized values of homeostasis model assessment, systolic blood pressure, triglycerides, total cholesterol/high-density lipoprotein cholesterol ratio, and leptin. Linear regression models indicated that CRF acted as an important and partial mediator in the association between fatness and CMRs in 12-17-year-old adolescents (for BMI: coefficients of the indirect role β = 0.058 (95% confidence interval (95%CI): 0.023-0.101), Sobel test z = 3.11 (10.0% mediation); for waist to height ratio: β = 4.279 (95%CI: 2.242-7.059), z =3.86 (11.5% mediation); and for fat mass index: β = 0.060 (95%CI: 0.020-0.106), z = 2.85 (9.4% mediation); all p < 0.01). In adolescents, the association between fatness and CMRs could be partially decreased with improvements to fitness levels; therefore, CRF contribution both in the clinical field and public health could be important to consider and promote in adolescents independently of their fatness levels.Show less >

Audience :

Non spécifiée

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2021-05-20T06:03:41Z
2021-05-21T07:24:28Z