Title :

Second autologous stem cell transplantation for relapsed/refractory hodgkin lymphoma after a previous autograft: a study of the lymphoma working party of the ebmt

Author(s) :

Martinez, Carmen [Auteur]
Boumendil, Ariane [Auteur]
Romejko-Jarosinska, Joanna [Auteur]
Anagnostopoulos, Achilles [Auteur]
Faber, Edgar [Auteur]
Poire, Xavier [Auteur]
Yakoub-Agha, Ibrahim [Auteur]
Akhtar, Saad [Auteur]
Gurman, Gunhan [Auteur]
Pavone, Vincenzo [Auteur]
Halaburda, Kazimierz [Auteur]
Sousa, Aida Botelho [Auteur]
Ghesquieres, Herve [Auteur]
Finel, Herve [Auteur]
Khvedelidze, Irma [Auteur]
Montoto, Silvia [Auteur]
Sureda, Anna [Auteur]

Journal title :

Leukemia & lymphoma

Abbreviated title :

Leuk. Lymphoma

Pages :

1-8

Publication date :

2020-07-11

ISSN :

1029-2403

Keyword(s) :

Hodgkin lymphoma
relapse
refractory
autologous hematopoietic stem cell transplantation

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

The purpose of this study was to analyze the results of second autologous hematopoietic stem cell transplantation (ASCT2) for patients with relapsed/refractory Hodgkin lymphoma (HL) after a first transplantation (ASCT1). ...
Show more >The purpose of this study was to analyze the results of second autologous hematopoietic stem cell transplantation (ASCT2) for patients with relapsed/refractory Hodgkin lymphoma (HL) after a first transplantation (ASCT1). Outcomes for 56 patients receiving an ASCT2 registered in the EBMT database were analyzed. The 4-year cumulative incidences of non-relapse mortality and disease relapse/progression were 5% and 67%, respectively. The 4-year overall survival (OS) and progression-free survival (PFS) were 62% and 28%. In univariate analysis, relapse of HL within 12 months of ASCT1 was associated with a worse OS (35% versus 76%, ppppShow less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2021-07-06T12:47:31Z