FDG PET/CT allowing detection and follow-up ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
FDG PET/CT allowing detection and follow-up of tumor cell transplantation
Auteur(s) :
Jaillard, Alice [Auteur]
Baillet, Clio [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 [GRITA]
Beron, Amandine [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Tabibzadeh, Nahid [Auteur]
Service de Néphrologie et Transplantation rénale [CHRU-lille]
Scherpereel, Arnaud [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 8204
Frimat, Marie [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Lille Inflammation Research International Center (LIRIC) - U995
Perbet, Romain [Auteur]
Service d'oncologie médicale (CHRU Lille)
Gnemmi, Viviane [Auteur]
CIC CHU ( Lille)/inserm
Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer (JPArc) - U1172
Noel, Christian [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Lille Inflammation Research International Center (LIRIC) - U995
Huglo, Damien [Auteur]
Thérapies Assistées par Lasers et Immunothérapies pour l'Oncologie - U 1189 [OncoThAI]
Thérapies Lasers Assistées par l'Image pour l'Oncologie (ONCO-THAI) - U1189
Baillet, Clio [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 [GRITA]
Beron, Amandine [Auteur]
Centre Hospitalier Régional Universitaire [CHU Lille] [CHRU Lille]
Tabibzadeh, Nahid [Auteur]
Service de Néphrologie et Transplantation rénale [CHRU-lille]
Scherpereel, Arnaud [Auteur]
Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL]
Centre d'Infection et d'Immunité de Lille (CIIL) - U1019 - UMR 8204
Frimat, Marie [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Lille Inflammation Research International Center (LIRIC) - U995
Perbet, Romain [Auteur]
Service d'oncologie médicale (CHRU Lille)
Gnemmi, Viviane [Auteur]
CIC CHU ( Lille)/inserm
Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer (JPArc) - U1172
Noel, Christian [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Lille Inflammation Research International Center (LIRIC) - U995
Huglo, Damien [Auteur]
Thérapies Assistées par Lasers et Immunothérapies pour l'Oncologie - U 1189 [OncoThAI]
Thérapies Lasers Assistées par l'Image pour l'Oncologie (ONCO-THAI) - U1189
Titre de la revue :
Annals of Nuclear Medicine
Nom court de la revue :
Ann. Nucl. Med.
Numéro :
30
Pagination :
250-254
Date de publication :
2016-04
ISSN :
0914-7187
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
After detection of small cell lung cancer in a 67-year-old patient who had donated a kidney 7 months earlier, the graft recipient underwent FDG-PET/CT to determine the presence/absence of tumor cell transmission. It showed ...
Lire la suite >After detection of small cell lung cancer in a 67-year-old patient who had donated a kidney 7 months earlier, the graft recipient underwent FDG-PET/CT to determine the presence/absence of tumor cell transmission. It showed abnormal increased uptake of the renal graft, associated with hypermetabolic lymph nodes and hepatic, pulmonary and bone lesions. Emergency graft resection was performed 5 days after PET/CT, permitting immunosuppressive therapy withdrawal. Pathologic examination of the kidney showed parenchymal infiltration by tumor cells compatible with small cell lung cancer. Thereafter, pathologists proved that the recipient's and donor's tumor cells matched using microsatellite markers. FDG-PET/CT was performed in the follow-up and showed progression in the donor despite chemotherapy and radiotherapy. He died a few months later. However, FDG-PET/CT showed a complete metabolic response after only 3 courses of chemotherapy in the recipient.Lire moins >
Lire la suite >After detection of small cell lung cancer in a 67-year-old patient who had donated a kidney 7 months earlier, the graft recipient underwent FDG-PET/CT to determine the presence/absence of tumor cell transmission. It showed abnormal increased uptake of the renal graft, associated with hypermetabolic lymph nodes and hepatic, pulmonary and bone lesions. Emergency graft resection was performed 5 days after PET/CT, permitting immunosuppressive therapy withdrawal. Pathologic examination of the kidney showed parenchymal infiltration by tumor cells compatible with small cell lung cancer. Thereafter, pathologists proved that the recipient's and donor's tumor cells matched using microsatellite markers. FDG-PET/CT was performed in the follow-up and showed progression in the donor despite chemotherapy and radiotherapy. He died a few months later. However, FDG-PET/CT showed a complete metabolic response after only 3 courses of chemotherapy in the recipient.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
CHU Lille
CNRS
Inserm
Institut Pasteur de Lille
CHU Lille
CNRS
Inserm
Institut Pasteur de Lille
Collections :
Équipe(s) de recherche :
Innovation/évaluation des médicaments injectables
Date de dépôt :
2019-02-26T17:07:29Z
2022-04-13T08:41:48Z
2022-04-13T08:41:48Z