Title :

The epidemiology of Budd-Chiari syndrome in France.

Author(s) :

Ollivier-Hourmand, Isabelle [Auteur]
Allaire, Manon [Auteur]
Goutte, Nathalie [Auteur]
Morello, Remy [Auteur]
Chagneau-Derrode, Carine [Auteur]
Goria, Odile [Auteur]
Dumortier, Jerome [Auteur]
Cervoni, Jean-Paul [Auteur]
Dharancy, Sebastien [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Ganne-Carrie, Nathalie [Auteur]
Génomique Fonctionnelle des Tumeurs Solides [U1162]
Bureau, Christophe [Auteur]
Carbonell, Nicolas [Auteur]
Abergel, Armand [Auteur]
Nousbaum, Jean-Baptiste [Auteur]
Anty, Rodolphe [Auteur]
Barraud, Helene [Auteur]
Ripault, Marie-Pierre [Auteur]
De Ledinghen, Victor [Auteur]
Minello, Anne [Auteur]
Oberti, Frederic [Auteur]
Radenne, Sylvie [Auteur]
Bendersky, Noelle [Auteur]
Farges, Olivier [Auteur]
Archambeaud, Isabelle [Auteur]
Guillygomarc'h, Anne [Auteur]
Ecochard, Marie [Auteur]
Ozenne, Violaine [Auteur]
Hilleret, Marie-Noelle [Auteur]
Nguyen-Khac, Eric [Auteur]
Dauvois, Barbara [Auteur]
Perarnau, Jean-Marc [Auteur]
Lefilliatre, Pascale [Auteur]
Raabe Jean, Jacques [Auteur]
Doffoel, Michel [Auteur]
Becquart Jean, Philippe [Auteur]
Saillard, Eric [Auteur]
Valla, Dominique [Auteur]
Université Paris Diderot - Paris 7 [UPD7]
Dao, Thong [Auteur]
Plessier, Aurelie [Auteur]

Journal title :

Digestive and Liver Disease

Abbreviated title :

Dig. Liver Dis.

Volume number :

50

Pages :

931-937

Publication date :

2018-09

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

INTRODUCTION: Epidemiological data is lacking on primary Budd-Chiari syndrome (BCS) in France. METHODS: Two approaches were used: (1) A nationwide survey in specialized liver units for French adults. (2) A query of the ...
Show more >INTRODUCTION: Epidemiological data is lacking on primary Budd-Chiari syndrome (BCS) in France. METHODS: Two approaches were used: (1) A nationwide survey in specialized liver units for French adults. (2) A query of the French database of discharge diagnoses screening to identify incident cases in adults. BCS associated with cancer, alcoholic/viral cirrhosis, or occurring after liver transplantation were classified as secondary. RESULTS: Approach (1) 178 primary BCS were identified (prevalence 4.04 per million inhabitants (pmi)), of which 30 were incident (incidence 0.68pmi). Mean age was 40+/-14yrs. Risk factors included myeloproliferative neoplasms (MPN) (48%), oral contraceptives (35%) and factor V Leiden (16%). None were identified in 21% of patients, >/=2 risk factors in 25%. BMI was higher in the group without any risk factor (25.7kg/m(2) vs 23.7kg/m(2), p<0.001). Approach (2) 110 incident primary BCS were admitted to French hospitals (incidence 2.17pmi). MPN was less common (30%) and inflammatory local factors predominated (39%). CONCLUSION: The entity of primary BCS as recorded in French liver units is 3 times less common than the entity recorded as nonmalignant hepatic vein obstruction in the hospital discharge database. The former entity is mostly related to MPN whereas the latter with abdominal inflammatory diseases.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Inserm
Université de Lille
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Research team(s) :

Inflammatory digestive disease : pathophysiology and therapeutic targets developement

Submission date :

2019-03-01T14:08:09Z
2024-01-30T10:17:09Z