Involvement of Mitochondrial Disorders in ...
Document type :
Article dans une revue scientifique: Article de synthèse/Review paper
DOI :
PMID :
Permalink :
Title :
Involvement of Mitochondrial Disorders in Septic Cardiomyopathy
Author(s) :
Durand, Arthur [Auteur]
Duburcq, Thibault [Auteur]
Dekeyser, Thibault [Auteur]
Nevière, Rémi [Auteur]
Howsam, Michael [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Favory, Raphael [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Preau, Sebastien [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Duburcq, Thibault [Auteur]
Dekeyser, Thibault [Auteur]
Nevière, Rémi [Auteur]
Howsam, Michael [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Favory, Raphael [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Preau, Sebastien [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Journal title :
Oxidative medicine and cellular longevity
Abbreviated title :
Oxidative Med. Cell. Longev.
Publication date :
2017-01-01
ISSN :
1942-0900
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It remains a leading cause of death worldwide, despite the development of various therapeutic strategies. ...
Show more >Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It remains a leading cause of death worldwide, despite the development of various therapeutic strategies. Cardiac dysfunction, also referred to as septic cardiomyopathy, is a frequent and well-described complication of sepsis and associated with worse clinical outcomes. Recent research has increased our understanding of the role of mitochondrial dysfunction in the pathophysiology of septic cardiomyopathy. The purpose of this review is to present this evidence as a coherent whole and to highlight future research directions.Show less >
Show more >Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It remains a leading cause of death worldwide, despite the development of various therapeutic strategies. Cardiac dysfunction, also referred to as septic cardiomyopathy, is a frequent and well-described complication of sepsis and associated with worse clinical outcomes. Recent research has increased our understanding of the role of mitochondrial dysfunction in the pathophysiology of septic cardiomyopathy. The purpose of this review is to present this evidence as a coherent whole and to highlight future research directions.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
Inserm
Université de Lille
CHU Lille
Université de Lille
CHU Lille
Research team(s) :
Glycation from inflammation to aging
Submission date :
2019-03-01T14:17:27Z