Title :

Accreditation of the toxicological screening: recommendations of the sfbc-sfta group

Author(s) :

Guitton, Jerome [Auteur]
Gaulier, Jean-Michel [Auteur]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Citterio-Quentin, Antony [Auteur]
Abe, Emuri [Auteur]
Allibe, Nathalie [Auteur]
Bartoli, Mireille [Auteur]
Cohen, Sabine [Auteur]
Monteil-Ganiere, Catherine [Auteur]
Garcia-Hejl, Carine [Auteur]
Grosjean, Jerome [Auteur]
Richard, Damien [Auteur]
Roman, Emilie [Auteur]
Saint-Marcoux, Franck [Auteur]
Wendremaire, Maeva [Auteur]

Journal title :

Annales de biologie clinique

Abbreviated title :

Ann. Biol. Clin. (Paris)

Volume number :

77

Pages :

219-224

Publisher :

John Libbey Eurotext

Publication date :

2019-04-01

ISSN :

1950-6112

Keyword(s) :

toxicological screening
ISO 15189
ISO standard
accreditation

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Toxicological screening is a specific approach to analytical toxicology that uses analytical tools such as GC-MS, LC-UV (diode array) or LC-MS. Toxicological screening allows the detection and simultaneous identification ...
Show more >Toxicological screening is a specific approach to analytical toxicology that uses analytical tools such as GC-MS, LC-UV (diode array) or LC-MS. Toxicological screening allows the detection and simultaneous identification of a large number of compounds. The results may be based on the use of one or more techniques. As part of the accreditation process for medical biology examinations according to standard NF EN ISO 15189, the group from SFTA and SFBC recommends an approach to accredit toxicological screening. Indeed, the complexity of the accreditation of this analysis comes in particular from the high number of compounds that can be detected. Validation parameters are discussed in the specific context of toxicological screening by considering two distinct approaches: the simple identification of compounds, or the identification and estimation of a range of concentration related to clinical outcomes.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CHU Lille
Institut Pasteur de Lille
Université de Lille

Collections :

• IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483

Submission date :

2022-02-02T10:23:57Z
2024-02-28T10:18:03Z