Accreditation of the toxicological screening: ...
Document type :
Article dans une revue scientifique: Article original
DOI :
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Title :
Accreditation of the toxicological screening: recommendations of the sfbc-sfta group
Author(s) :
Guitton, Jerome [Auteur]
Gaulier, Jean-Michel [Auteur]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Citterio-Quentin, Antony [Auteur]
Abe, Emuri [Auteur]
Allibe, Nathalie [Auteur]
Bartoli, Mireille [Auteur]
Cohen, Sabine [Auteur]
Monteil-Ganiere, Catherine [Auteur]
Garcia-Hejl, Carine [Auteur]
Grosjean, Jerome [Auteur]
Richard, Damien [Auteur]
Roman, Emilie [Auteur]
Saint-Marcoux, Franck [Auteur]
Wendremaire, Maeva [Auteur]
Gaulier, Jean-Michel [Auteur]
Impact de l'environnement chimique sur la santé humaine - ULR 4483 [IMPECS]
Citterio-Quentin, Antony [Auteur]
Abe, Emuri [Auteur]
Allibe, Nathalie [Auteur]
Bartoli, Mireille [Auteur]
Cohen, Sabine [Auteur]
Monteil-Ganiere, Catherine [Auteur]
Garcia-Hejl, Carine [Auteur]
Grosjean, Jerome [Auteur]
Richard, Damien [Auteur]
Roman, Emilie [Auteur]
Saint-Marcoux, Franck [Auteur]
Wendremaire, Maeva [Auteur]
Journal title :
Annales de biologie clinique
Abbreviated title :
Ann. Biol. Clin. (Paris)
Volume number :
77
Pages :
219-224
Publisher :
John Libbey Eurotext
Publication date :
2019-04-01
ISSN :
1950-6112
Keyword(s) :
toxicological screening
ISO 15189
ISO standard
accreditation
ISO 15189
ISO standard
accreditation
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
Toxicological screening is a specific approach to analytical toxicology that uses analytical tools such as GC-MS, LC-UV (diode array) or LC-MS. Toxicological screening allows the detection and simultaneous identification ...
Show more >Toxicological screening is a specific approach to analytical toxicology that uses analytical tools such as GC-MS, LC-UV (diode array) or LC-MS. Toxicological screening allows the detection and simultaneous identification of a large number of compounds. The results may be based on the use of one or more techniques. As part of the accreditation process for medical biology examinations according to standard NF EN ISO 15189, the group from SFTA and SFBC recommends an approach to accredit toxicological screening. Indeed, the complexity of the accreditation of this analysis comes in particular from the high number of compounds that can be detected. Validation parameters are discussed in the specific context of toxicological screening by considering two distinct approaches: the simple identification of compounds, or the identification and estimation of a range of concentration related to clinical outcomes.Show less >
Show more >Toxicological screening is a specific approach to analytical toxicology that uses analytical tools such as GC-MS, LC-UV (diode array) or LC-MS. Toxicological screening allows the detection and simultaneous identification of a large number of compounds. The results may be based on the use of one or more techniques. As part of the accreditation process for medical biology examinations according to standard NF EN ISO 15189, the group from SFTA and SFBC recommends an approach to accredit toxicological screening. Indeed, the complexity of the accreditation of this analysis comes in particular from the high number of compounds that can be detected. Validation parameters are discussed in the specific context of toxicological screening by considering two distinct approaches: the simple identification of compounds, or the identification and estimation of a range of concentration related to clinical outcomes.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
Institut Pasteur de Lille
Université de Lille
Institut Pasteur de Lille
Université de Lille
Submission date :
2022-02-02T10:23:57Z
2024-02-28T10:18:03Z
2024-02-28T10:18:03Z
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