Title :

Continuous hydroformylation of 1-decene in an aqueous biphasic system enabled by methylated cyclodextrins

Author(s) :

Kuenneman, n K. U. [Auteur]
Schurm, L. [Auteur]
Lange, D. [Auteur]
Seidensticker, T. [Auteur]
Tilloy, Sebastien [Auteur]
UCCS Équipe Catalyse Supramoléculaire
Monflier, Eric [Auteur]
UCCS Équipe Catalyse Supramoléculaire
Vogt, D. [Auteur]
Dreimann, J. M. [Auteur]

Journal title :

Green chemistry . an international journal and green chemistry resource . GC

Abbreviated title :

Green Chem.

Volume number :

22

Pages :

3809-3819

Publication date :

2020-06-21

ISSN :

1463-9262

HAL domain(s) :

Chimie/Catalyse

English abstract : [en]

For the first time, randomly methylated β-cyclodextrin was applied as the mass transfer agent in a continuous process. Considering the example of the Rh-catalyzed hydroformylation of 1-decene, process development was shown, ...
Show more >For the first time, randomly methylated β-cyclodextrin was applied as the mass transfer agent in a continuous process. Considering the example of the Rh-catalyzed hydroformylation of 1-decene, process development was shown, where cyclodextrin was used together with a catalyst system that was continuously recovered and recycled using an aqueous biphasic system. In initial experiments, water-soluble and commercially available Rh/TPPTS and Rh/sulfoxantphos catalyst systems were scaled up from 50 ml into 1000 ml high-pressure autoclave systems to demonstrate their scalability. Both these systems were compared, and they afforded excellent chemoselectivity (>99%) toward the desired linear aldehyde product. In particular, higher regioselectivity (up to 31) was achieved for the Rh/sulfoxantphos system. Investigations regarding the long-term stability of the mass transfer agent and both catalyst systems were carried out in a continuously operated miniplant process. It was shown that the process could be successfully operated under the steady state for over 200 h with chemoselectivity of >97% toward the desired aldehyde product. Simultaneously, extremely low Rh leaching (total: 0.59%) was observed over the entire period of 200 h.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

CNRS
Centrale Lille
ENSCL
Univ. Artois
Université de Lille

Collections :

• Unité de Catalyse et Chimie du Solide (UCCS) - UMR 8181

Research team(s) :

Catalyse et chimie supramoléculaire (CASU)

Submission date :

2022-03-02T07:13:19Z
2023-12-15T19:46:27Z