Titre :

Which characteristics and circumstances of exercise do expose to hypo/hyperglycaemic risk and glycaemic variability in children and adolescents with type 1 diabetes: a daily life observational study controlling for confounding impact of food intake and insulin administration

Auteur(s) :

Melin, Angeline [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369
Lespagnol, Elodie [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369
Heyman, Joris [Auteur]
Morel, Pierre [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Deureumetz, Julie [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Coquart, A [Auteur]
Stuckens, C [Auteur]
Lefevre, C [Auteur]
Berthoin, Serge [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369
Baquet, Georges [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369
Tagougui, Sémah [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369
Heyman, Elsa [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369

Titre de la manifestation scientifique :

Symposium Diabète de type 1 & Exercice physique : de la gestion des risques aux bénéfices pour la santé

Organisateur(s) de la manifestation scientifique :

Elsa Heyman

Ville :

Lille

Date de début de la manifestation scientifique :

2023-03-29

Résumé en anglais : [en]

Background: Blood glucose levels in people with type 1 diabetes (T1D) are mainly influenced by food intake and exogenous insulin. The addition of physical activity (PA) of daily living can disrupt the glucose balance and ...
Lire la suite >Background: Blood glucose levels in people with type 1 diabetes (T1D) are mainly influenced by food intake and exogenous insulin. The addition of physical activity (PA) of daily living can disrupt the glucose balance and cause hypoglycaemic but also, in some circumstances, hyperglycaemic excursions (1) which both represent major barriers to PA commitment (2). The aim of the study was to understand the influence of the characteristics of daily- life PA sessions and their circumstances on glycaemia. Methods: Fifty-eight children/adolescents (11.7 ± 3.4 years) wore a uniaxial accelerometer and a continuous glucose monitoring system for 7 days. During this daily-life week, participants fill in a diary to report their structured PA sessions (time, type, duration and subjective intensity), their diet and insulin data. Multiple linear regressions and multinomial logistic regressions were used to explore link between characteristics of PA and glycaemia (during PA, 2 hours of recovery and the subsequent night), controlling for initial glycaemia, carbohydrate intake, insulin administered, time of the day, and individual characteristics. Results: Time spent in moderate-to-vigorous PA (MVPA, by accelerometery) (e +0.04; P=0,07) and even more the duration of reported sessions (e +0.02; P<0,01) were predictors of increased time spent <70mg.dL-1 during exercise, whereas this risk was logically reduced with higher initial glycaemia. Both exercise duration and MVPA were also predictive of increased time in level 2 hypoglycaemia (<54mg.dL-1) during the following night (e> +0.02; P<0.03). In addition, during early recovery, this risk was greater for exercises performed in the afternoon vs. morning (e> +1.3; P <0.05). Concerning hyperglycaemia, starting PA far away from a bolus (e + 0.05; P=0.02 for exercise duration; e +0.04; P=0.09 for MVPA) or after consuming high glycaemic index carbohydrates in the previous hour (e +0.48; P<0.02 for exercise duration; e +0.38, P<0.08 for MVPA) were associated with a longer time > 180mg.dL-1 during the exercise sessions. However, if the children did another session on the same day before the current exercise, this risk of hyperglycaemia was prevented (e<−11.4; P<0.03). Conclusion: Compared with objectively measured MVPA, self-reported duration of PA was at least as well accurate predictor of the risk of hypoglycaemia during exercise and late recovery, which can thus be useful in practice. Besides, adjusting the time from the last insulin bolus and the high glycaemic index carbohydrates one hour before exercise might be effective strategies for preventing hyperglycaemia during exercise.Lire moins >

Comité de lecture :

Oui

Audience :

Internationale

Établissement(s) :

Université de Lille
Univ. Artois
Univ. Littoral Côte d’Opale

Collections :

• Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369

Équipe(s) de recherche :

Activité Physique, Muscle, Santé (APMS)

Date de dépôt :

2023-04-02T09:41:02Z