Titre :

Lavandula pedunculata (Mill.) Cav. Aqueous Extract Antibacterial Activity Improved by the Addition of Salvia rosmarinus Spenn., Salvia lavandulifolia Vahl and Origanum compactum Benth.

Auteur(s) :

Boutahiri, Salima [Auteur]
BioEcoAgro - UMR transfrontalière INRAe - UMRT1158
Eto, Bruno [Auteur]
Université de Lille
Bouhrim, Mohamed [Auteur]
Saleh, Asmaa [Auteur]
Al Kamaly, Omkulthom [Auteur]
Drioiche, Aziz [Auteur]
Remok, Firdaous [Auteur]
Samaillie, Jennifer [Auteur]
BioEcoAgro - UMR-T 1158
Institut Charles Viollette (ICV) - ULR 7394
Neut, Christel [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Gressier, Bernard [Auteur]
Lille Neurosciences & Cognition (LilNCog) - U 1172
Kouoh Elombo, Ferdinand [Auteur]
Nassiri, Laila [Auteur]
Zair, Touriya [Auteur]
Sahpaz, Sevser [Auteur]
BioEcoAgro - UMR-T 1158
Institut Charles Viollette (ICV) - ULR 7394

Titre de la revue :

Life

Nom court de la revue :

Life (Basel)

Numéro :

12

Pagination :

328

Date de publication :

2022-03-30

ISSN :

2075-1729

Mot(s)-clé(s) en anglais :

Lavandula pedunculata (Mill
) Cav
Salviarosmarinus Spenn
Salvia lavandulifolia Vahl
Origanum compactum Benth
polyphenols
antibacterial activity

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Lavender aqueous extracts are widely used in the Moroccan traditional medicine for their antibacterial properties. However, previous research have generally focused on investigating the antibacterial activity of lavender ...
Lire la suite >Lavender aqueous extracts are widely used in the Moroccan traditional medicine for their antibacterial properties. However, previous research have generally focused on investigating the antibacterial activity of lavender essential oils. The aim of this study is to evaluate the antibacterial activity of the Moroccan Lavandula pedunculata (Mill.) Cav. aqueous extract, alone, as well as in combination with extracts of other plant species known for their antibacterial activity: Salvia rosmarinus Spenn., Salvia lavandulifolia Vahl. and Origanum compactum Benth. We have tested the antibacterial activity of L. pedunculata, S. rosmarinus, S. lavandulifolia and O. compactum aqueous extracts individually and in combination against 34 strains using the agar dilution method. The combination effect was evaluated using the fractional inhibitory concentration (FIC). Polyphenol and tannin contents were determined using Folin-Ciocalteu reagent, and then some phenolic compounds were identified using UHPLC-MS. All the extracts displayed a large spectrum of antibacterial activity, especially against staphylococci, streptococci, Mycobacterium smegmatis and Proteus mirabilis. The minimum inhibitory concentration (MIC) values reached 0.15 ± 0.00 mg/mL for Staphylococcus warneri tested with S. lavandulifolia and 0.20 ± 0.07 mg/mL for Staphylococcus epidermidis tested with L. pedunculata or S. rosmarinus. Association of the L. pedunculata extract with S. rosmarinus, S. lavandulifolia and O. compactum showed synergistic effects (FIC ≤ 1). Moreover, the association of L. pedunculata with S. lavandulifolia was active against most of the Gram-negative strains resistant to the individual extracts. Determination of polyphenol and tannin contents showed the richness of the studied plants in these compounds. Additionally, chromatographic analysis demonstrated the high presence of rosmarinic acid in all the studied plant extracts. To our knowledge, this is the first study that shows the enhancing effect of the antibacterial activity of L. pedunculata aqueous extract combined with S. rosmarinus, S. lavandulifolia and O. compactum. These results confirm the effectiveness of the plant mixtures commonly used by traditional healers in Morocco and suggest that L. pedunculata might be used as an antibacterial agent either alone or, more efficiently, in combination with S. rosmarinus, S. lavandulifolia and O. compactum.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• BioEcoAgro - UMR-T 1158
• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
• Lille Neurosciences & Cognition (LilNCog) - U 1172

Date de dépôt :

2024-01-12T02:00:48Z
2024-03-14T14:28:58Z