Title :

Prevalence of Self-Reported Venous Thromboembolism and Cardiovascular Risk Factors in Patients with Ulcerative Colitis: The GETAID FOCUS Study.

Author(s) :

Guillo, Lucas [Auteur]
Assistance Publique - Hôpitaux de Marseille [APHM]
Amiot, Aurélien [Auteur]
Early detection of Colon Cancer using Molecular Markers and Microbiota (EA 7375) [EC2M3]
Serrero, Mélanie [Auteur]
Aix Marseille Université [AMU]
Altwegg, Romain [Auteur]
Centre Hospitalier Régional Universitaire [Montpellier] [CHRU Montpellier]
Roblin, Xavier [Auteur]
Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] [CHU ST-E]
Atanasiu, Calina [Auteur]
Buisson, Anthony [Auteur]
Infection Inflammation et Interaction Hôtes Pathogènes [CHU Clermont-Ferrand] [3IHP ]
Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte [M2iSH]
Le Berre, Catherine [Auteur]
Centre d'investigation clinique (CIC) de Nantes -CIC Plurithématique [CIC 0004 - Nantes]
Reenaers, Catherine [Auteur]
Université de Liège
Gornet, Jean-Marc [Auteur]
Hopital Saint-Louis [AP-HP] [AP-HP]
Laharie, David [Auteur]
Université de Bordeaux [UB]
Abitbol, Vered [Auteur]
Hôpital Cochin [AP-HP]
Biron, Amélie [Auteur]
Hôpital universitaire Robert Debré [Reims] [CHU Reims]
Caron, Bénédicte [Auteur]
Interface de Recherche Fondamentale et Appliquée en Cancérologie [IRFAC - Inserm U1113]
Nancey, Stéphane [Auteur]
Centre International de Recherche en Infectiologie [CIRI]
Chupin, Antoine [Auteur]
Université Paris-Saclay
Blain, Antoine [Auteur]
Institut Mutualiste de Montsouris [IMM]
Vuitton, Lucine [Auteur]
Centre Hospitalier Régional Universitaire de Besançon [CHRU Besançon]
Caillo, Ludovic [Auteur]
Centre Hospitalier Universitaire de Nîmes [CHU Nîmes]
Kirchgesner, Julien [Auteur]
Institut Pierre Louis d'Epidémiologie et de Santé Publique [iPLESP]
Nachury, Maria [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Peyrin-Biroulet, Laurent [Auteur]
Nutrition-Génétique et Exposition aux Risques Environnementaux [NGERE]

Journal title :

Digestive Diseases and Sciences

Abbreviated title :

Dig Dis Sci

Volume number :

67

Pages :

4525–4532

Publication date :

2022-03-12

ISSN :

1573-2568

English keyword(s) :

Ulcerative colitis
Heart disease risk factors
Disease progression
Venous thromboembolism

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Background and Aims Patients with inflammatory bowel disease have an increased risk of venous thromboembolism (VTE) and cardiovascular disease (CVD). The study aims to determine the prevalence of CVD and VTE risk factors ...
Show more >Background and Aims Patients with inflammatory bowel disease have an increased risk of venous thromboembolism (VTE) and cardiovascular disease (CVD). The study aims to determine the prevalence of CVD and VTE risk factors in a large population of patients with ulcerative colitis (UC). Methods We conducted a cross-sectional study in 33 French and Belgium referral centers. A questionnaire was developed to explore self-reported risk factors for VTE and CVD, based on the latest international guidelines, in consecutive patients with UC. Results A total of 1071 patients with UC were included. There were 539 women (50.3%), and the median age of patients was 44 years [32; 57]. The median disease duration was 10 years [6; 17]. In the cohort, 36.5% of patients reported no cardiovascular risk factor (CVRF) and 72% had ≤ 1 CVRF. Regarding cardiovascular risk markers (CVRM) 36.9% of patients reported no CVRM and 78% had ≤ 1 CVRM. Of the 1071 patients, 91.3% of patients reported no VTE strong risk factor and 96% had ≤ 1 VTE moderate risk factor. Conclusion This is the first cohort specifically designed to assess both VTE and CVD risks in patients with UC. More than one third of patients with UC had no CVRF and around three quarters had ≤ 1 CVRF. In addition, more than nine out of ten patients had no VTE strong risk factor and ≤ 1 moderate risk factor. Physicians should be aware of these factors in their patients.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2024-01-12T02:08:16Z
2024-03-22T13:46:26Z