Dramatic increase in incidence of ulcerative ...
Type de document :
Article dans une revue scientifique: Article original
DOI :
PMID :
URL permanente :
Titre :
Dramatic increase in incidence of ulcerative colitis and crohn''s disease (1988-2011): a population-based study of french adolescents
Auteur(s) :
Ghione, Silvia [Auteur]
Sarter, Helene [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Fumery, Mathurin [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Armengol-Debeir, Laura [Auteur]
Savoye, Guillaume [Auteur]
Ley, Delphine [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Spyckerelle, Claire [Auteur]
Hôpital Saint Vincent de Paul de Lille
Pariente, Benjamin [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Peyrin-Biroulet, Laurent [Auteur]
Turck, Dominique [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Gower, Corinne [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Sarter, Helene [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Fumery, Mathurin [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Armengol-Debeir, Laura [Auteur]
Savoye, Guillaume [Auteur]
Ley, Delphine [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Spyckerelle, Claire [Auteur]
Hôpital Saint Vincent de Paul de Lille
Pariente, Benjamin [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Peyrin-Biroulet, Laurent [Auteur]
Turck, Dominique [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Gower, Corinne [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Titre de la revue :
The American Journal of Gastroenterology
Nom court de la revue :
Am. J. Gastroenterol.
Numéro :
113
Pagination :
265-272
Date de publication :
2018-02
ISSN :
0002-9270
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Few data are available to describe the changes in incidence of pediatric-onset inflammatory bowel disease (IBD). The aim of this study was to describe changes in incidence and phenotypic presentation of pediatric-onset IBD ...
Lire la suite >Few data are available to describe the changes in incidence of pediatric-onset inflammatory bowel disease (IBD). The aim of this study was to describe changes in incidence and phenotypic presentation of pediatric-onset IBD in northern France during a 24-year period. Pediatric-onset IBD (<17 years) was issued from a population-based IBD study in France between 1988 and 2011. Age groups and digestive location were defined according to the Paris classification. 1,350 incident cases were recorded (8.3% of all IBD) including 990 Crohn's disease (CD), 326 ulcerative colitis (UC) and 34 IBD unclassified (IBDU). Median age at diagnosis was similar in CD (14.4 years (Q1=11.8-Q3=16.0)) and UC (14.0 years (11.0-16.0)) and did not change over time. There were significantly more males with CD (females/males=0.82) than UC (females/males=1.25) (P=0.0042). Median time between onset of symptoms and IBD diagnosis was consistently 3 months (1-6). Mean incidence was 4.4/10555 In this population-based study, CD and UC incidences increased dramatically in adolescents across a 24-year span, suggesting that one or more strong environmental factors may predispose this population to IBD.Lire moins >
Lire la suite >Few data are available to describe the changes in incidence of pediatric-onset inflammatory bowel disease (IBD). The aim of this study was to describe changes in incidence and phenotypic presentation of pediatric-onset IBD in northern France during a 24-year period. Pediatric-onset IBD (<17 years) was issued from a population-based IBD study in France between 1988 and 2011. Age groups and digestive location were defined according to the Paris classification. 1,350 incident cases were recorded (8.3% of all IBD) including 990 Crohn's disease (CD), 326 ulcerative colitis (UC) and 34 IBD unclassified (IBDU). Median age at diagnosis was similar in CD (14.4 years (Q1=11.8-Q3=16.0)) and UC (14.0 years (11.0-16.0)) and did not change over time. There were significantly more males with CD (females/males=0.82) than UC (females/males=1.25) (P=0.0042). Median time between onset of symptoms and IBD diagnosis was consistently 3 months (1-6). Mean incidence was 4.4/10555 In this population-based study, CD and UC incidences increased dramatically in adolescents across a 24-year span, suggesting that one or more strong environmental factors may predispose this population to IBD.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
CHU Lille
Inserm
Université de Lille
Inserm
Université de Lille
Date de dépôt :
2024-01-30T10:26:31Z
2024-03-07T12:34:17Z
2024-03-07T12:34:17Z