Title :

Obesity in adult patients with inflammatory bowel disease: Clinical features and impact on disability. A cross-sectional survey from the GETAID.

Author(s) :

Bacha, Rose Al [Auteur]
Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre]
Bouhnik, Yoram [Auteur]
Hôpital Beaujon [AP-HP]
Serrero, Melanie [Auteur]
Aix Marseille Université [AMU]
Filippi, Jerome [Auteur]
Université Côte d'Azur [UniCA]
Roblin, Xavier [Auteur]
Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] [CHU ST-E]
Bourrier, Anne [Auteur]
CHU Saint-Antoine [AP-HP]
Bouguen, Guillaume [Auteur]
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Franchimont, Denis [Auteur]

Savoye, Guillaume [Auteur]
CHU Rouen
Buisson, Anthony [Auteur]
CHU Clermont-Ferrand
Louis, Edouard [Auteur]
Centre Hospitalier Universitaire de Liège [CHU-Liège]
Nancey, Stephane [Auteur]
Hospices Civils de Lyon [HCL]
Abitbol, Vered [Auteur]
Hôpital Cochin [AP-HP]
Reimund, Jean-Marie [Auteur]

Dewit, Olivier [Auteur]
Cliniques Universitaires Saint-Luc [Bruxelles]
Vuitton, Lucine [Auteur]
Centre Hospitalier Régional Universitaire de Besançon [CHRU Besançon]
Mathieu, Nicolas [Auteur]
Centre Hospitalier Universitaire [CHU Grenoble] [CHUGA]
Peyrin-Biroulet, Laurent [Auteur]
Nutrition-Génétique et Exposition aux Risques Environnementaux [NGERE]
Gilletta, Cyrielle [Auteur]
Centre Hospitalier Universitaire de Toulouse [CHU Toulouse]
Allez, Matthieu [Auteur]
Hopital Saint-Louis [AP-HP] [AP-HP]
Viennot, Stephanie [Auteur]
CHU Caen
Le Berre, Catherine [Auteur]
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital [CHU Nantes]
Laharie, David [Auteur]

Nachury, Maria [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Amiot, Aurelien [Auteur]

Journal title :

Digestive and Liver Disease

Abbreviated title :

Dig Liver Dis

Publication date :

2023-05-30

ISSN :

1878-3562

English abstract : [en]

Background: In recent years, an increasing prevalence of obesity in inflammatory bowel disease (IBD) has been observed. However, only a few studies have focused on the impact of overweight and obesity on IBD-related ...
Show more >Background: In recent years, an increasing prevalence of obesity in inflammatory bowel disease (IBD) has been observed. However, only a few studies have focused on the impact of overweight and obesity on IBD-related disability.Aims: To identify the factors associated with obese and overweight patients with IBD, including IBD-related disability.Patients and methods: In this cross-sectional study, we included 1704 consecutive patients with IBD in 42 centres affiliated with the Groupe d'Etude Therapeutique des Affections Inflammatoires du tube Digestif (GETAID) using a 4-page questionnaire. Factors associated with obesity and overweight were assessed using univariate and multivariate analyses (odds ratios (ORs) are provided with 95% confidence intervals).Results: The prevalence rates of overweight and obesity were 24.1% and 12.2%, respectively. Multivariable analyses were stratified by age, sex, type of IBD, clinical remission and age at diagnosis of IBD. Overweight was significantly associated with male sex (OR = 0.52, 95% CI [0.39-0.68], p < 0.001), age (OR = 1.02, 95% CI [1.01-1.03], p < 0.001) and body image subscore (OR = 1.15, 95% CI [1.10-1.20], p < 0.001) (Table 2). Obesity was significantly associated with age (OR = 1.03, 95% CI [1.02-1.04], p < 0.001), joint pain subscore (OR = 1.08, 95% CI [1.02-1.14], p < 0.001) and body image subscore (OR = 1.25, 95% CI [1.19-1.32], p < 0.001) (Table 3).Conclusion: The increasing prevalence of overweight and obesity in patients with IBD is associated with age and poorer body image. A holistic approach to IBD patient care should be encouraged to improve IBD-related disability and to prevent rheumatological and cardiovascular complications.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Submission date :

2024-01-30T22:08:34Z
2024-03-11T12:36:17Z