Titre :

Quality of life of inflammatory bowel diseases patients in france with EQ-5D-5 L: the QALY-MICI study

Auteur(s) :

Sarter, Helene [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Kirschgesner, J. [Auteur]
Beaugerie, L. [Auteur]
Buisson, A. [Auteur]
Gower, Corinne [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
De Pouvourville, G. [Auteur]

Titre de la revue :

Quality of Life Research

Nom court de la revue :

Qual. Life Res.

Numéro :

-

Pagination :

-

Éditeur :

Springer

Date de publication :

2024-11-18

ISSN :

0962-9343

Mot(s)-clé(s) en anglais :

EQ-5D-5L
France
Inflammatory bowel disease
Utility values

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Purpose This study aimed to document utility values and the Visual Analog Scale (VAS) with the 5-level version of the EQ-5D questionnaire in a large sample of patients with inflammatory bowel disease (IBD), including ...
Lire la suite >Purpose This study aimed to document utility values and the Visual Analog Scale (VAS) with the 5-level version of the EQ-5D questionnaire in a large sample of patients with inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC). Methods QALY-MICI was a cross-sectional survey across three sources in France. Data were collected between 2019 and 2022 for patients 18 and over. The EQ-5D-5 L, the EQ-VAS, the Short Inflammatory Bowel Disease Questionnaire (SIBDQ), the Harvey-Bradshaw Index (HBI) for CD, and the Walmsley Index for UC (SCCAI) were collected. Results A total of 2,841 patients aged over 18 were recruited (1785 with CD, 1056 with UC). The mean age was 40.2 (SD 14.3). The time since diagnosis was 6 years and over for 61.9% of patients. The most impacted dimensions were usual activities, anxiety/ depression, and pain/ discomfort. The mean utility value was 0.863 (SD 0.172) versus 0.905 (SD 0.158) in the French population (p = 0.007). The mean VAS value was 68 (SD 19.2) versus 73.4 (SD 22.2) in the general population (p = 0.016). Utility values and VAS were similar for CD and UC and higher for men. There was a strong positive correlation between utility values, the VAS, and the SIBDQ score, and a negative correlation between the HBI and the SCCAI. The SIBDQ score and disease activity were the main predictors of utility and VAS. Conclusion The QALY-MICI is, to our knowledge, the first study documenting utility values and VAS using the EQ-5D-5 L questionnaire on a large sample, with a comparison to the general population.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Date de dépôt :

2025-01-07T22:04:12Z
2025-01-15T09:51:05Z