Titre :

Patient acceptable symptom state and minimal clinically important difference for patient-reported outcomes in systemic sclerosis: A secondary analysis of a randomized controlled trial comparing personalized physical therapy to usual care.

Auteur(s) :

Daste, Camille [Auteur]
Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité [CRESS (U1153 / UMR_A_1125 / UMR_S_1153)]
Rannou, François [Auteur]
Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire [T3S - UMR_S 1124]
Mouthon, Luc [Auteur]
Université Paris Descartes - Paris 5 [UPD5]
Sanchez, Katherine [Auteur]
Roren, Alexandra [Auteur]
Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité [CRESS (U1153 / UMR_A_1125 / UMR_S_1153)]
Tiffreau, Vincent [Auteur]
Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369 - ULR 4488 [URePSSS]
Hachulla, Eric [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Thoumie, Philippe [Auteur]
Université Pierre et Marie Curie - Paris 6 [UPMC]
Cabane, Jean [Auteur]
Chatelus, Emmanuel [Auteur]
Université de Strasbourg [UNISTRA]
Sibilia, Jean [Auteur]
Université de Strasbourg [UNISTRA]
Poiraudeau, Serge [Auteur]
Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité [CRESS (U1153 / UMR_A_1125 / UMR_S_1153)]
Nguyen, Christelle [Auteur]
Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire [T3S - UMR_S 1124]

Titre de la revue :

Seminars in Arthritis and Rheumatism

Nom court de la revue :

Semin. Arthritis Rheum.

Numéro :

48

Pagination :

694-700

Date de publication :

2019-02

ISSN :

1532-866X

Mot(s)-clé(s) en anglais :

Minimal clinically important difference
Patient acceptable symptom state
Systemic sclerosis
Patient-reported outcomes

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

To estimate patient acceptable symptom state (PASS) and minimal clinically important difference (MCID) for patient-reported outcomes in systemic sclerosis (SSc). We conducted a secondary analysis of the SCLEREDUC trial, ...
Lire la suite >To estimate patient acceptable symptom state (PASS) and minimal clinically important difference (MCID) for patient-reported outcomes in systemic sclerosis (SSc). We conducted a secondary analysis of the SCLEREDUC trial, a 12-month randomized controlled trial comparing the efficacy of physical therapy to usual care in 220 SSc patients followed-up from September 2005 to October 2010. Self-rated state and change in patient health at 12 months were assessed by using 2 external anchors extracted from the Medical Outcomes Study 36-Item Short-Form. Patients who self-rated their health as "excellent", "very good" or "good" were the PASS group and those who self-rated their health change as "somewhat better" were the MCID group. Main outcomes were the estimates of PASS by using the 75th percentile method and of MCID by using the mean change in scores method for pain and activity limitation. PASS (95% confidence interval) and mean (SD) MCID estimates at 12 months were 53.75 (34.00 to 68.00) and -6.74 (32.02) for the joint-pain visual analog scale (range 0-100), 1.41 (1.13 to 1.63) and -0.21 (0.48) for the Health Assessment Questionnaire (HAQ, range 0-3), 1.27 (1.07 to 1.62) and -0.13 (0.45) for the scleroderma HAQ (range 0-3), 26.00 (17.00 to 37.00) and -3.38 (9.87) for the Cochin Hand Function Scale (range 0-90), and 19.40 (17.20 to 21.90) and -5.69 (6.79) for the McMaster-Toronto Arthritis Patient Preference Disability Questionnaire (range 0-30), respectively. We provide, for the first time, the PASS and MCID estimates for pain and activity limitation in SSc. ClinicalTrials.gov Identifier: NCT00318188. First Posted: April 26, 2006.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Univ. Littoral Côte d’Opale
Univ. Artois
Université de Lille
Inserm

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
• Unité de Recherche Pluridisciplinaire Sport, Santé, Société (URePSSS) - ULR 7369

Équipe(s) de recherche :

Activité Physique, Muscle, Santé (APMS)

Date de dépôt :

2019-09-24T10:01:40Z
2024-01-25T13:22:39Z