Titre :

Time to conversion to an everolimus-based regimen: renal outcomes in liver transplant recipients from the everoliver registry

Auteur(s) :

Saliba, Faouzi [Auteur]
Dharancy, Sebastien [Auteur]
Salame, Ephrem [Auteur]
Conti, Filomena [Auteur]
Eyraud, Daniel [Auteur]
Radenne, Sylvie [Auteur]
Antonini, Teresa [Auteur]
Guillaud, Olivier [Auteur]
Gugenheim, Jean [Auteur]
Neau-Cransac, Martine [Auteur]
De Martin, Eleonora [Auteur]
Lassailly, Guillaume [Auteur]
Duvoux, Christophe [Auteur]
Sobesky, Rodolphe [Auteur]
Coilly, Audrey [Auteur]
Tresson, Sylvie [Auteur]
Cailliez, Valerie [Auteur]
Boillot, Olivier [Auteur]
Pageaux, Georges-Philippe [Auteur]
Samuel, Didier [Auteur]
Calmus, Yvon [Auteur]
Dumortier, Jerome [Auteur]

Titre de la revue :

Liver transplantation . official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Nom court de la revue :

Liver Transpl.

Date de publication :

2020-08-31

ISSN :

1527-6473

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Longterm use of a calcineurin inhibitor (CNI)-based regimen is one of the major reasons for chronic renal failure in liver transplantation recipients (LTRs). The Everolimus Liver registry (EVEROLIVER) evaluated renal ...
Lire la suite >Longterm use of a calcineurin inhibitor (CNI)-based regimen is one of the major reasons for chronic renal failure in liver transplantation recipients (LTRs). The Everolimus Liver registry (EVEROLIVER) evaluated renal function in LTRs who were converted to everolimus (EVR). This observational registry included all LTRs receiving EVR across 9 centers from France. Data are being collected in an electronic database over 10 years (12 visits/patient) to evaluate efficacy, renal function (estimated glomerular filtration rate [eGFR]), and safety of EVR use in clinical practice, and the current analysis is reporting up to 60 months of findings. Until September 2017, 1045 patients received EVR after a mean time of 3.6 ± 5.1 years. CNI withdrawal was feasible in 57.7% of patients as of month 60. Mean eGFR improved in patients with baseline eGFR <60 mL/minute/1.73 m22222Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Date de dépôt :

2021-07-06T12:45:56Z