Titre :

Low incidence of sars-cov-2, risk factors of mortality and the course of illness in the french national cohort of dialysis patients

Auteur(s) :

Couchoud, Cecile [Auteur]
Agence de la biomédecine [Saint-Denis la Plaine]
Bayer, Florian [Auteur]
Agence de la biomédecine [Saint-Denis la Plaine]
Ayav, Carole [Auteur]
Centre d'investigation clinique - Epidémiologie clinique [Nancy] [CIC-EC]
Bechade, Clemence [Auteur]
Service de Néphrologie-Dialyse-Transplantation rénale [CHU Caen]
Brunet, Philippe [Auteur]
Centre de néphrologie et transplantation rénale [Hôpital de la Conception - APHM]
Chantrel, Francois [Auteur]
Centre Hospitalier Emile Muller [Mulhouse] [CH E.Muller Mulhouse]
Frimat, Luc [Auteur]
Centre Hospitalier Régional Universitaire de Nancy [CHRU Nancy]
Galland, Roula [Auteur]
Hourmant, Maryvonne [Auteur]
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital [CHU Nantes]
Laurain, Emmanuelle [Auteur]
Centre Hospitalier Régional Universitaire de Nancy [CHRU Nancy]
Lobbedez, Thierry [Auteur]
CHU Caen
Mercadal, Lucile [Auteur]
CHU Pitié-Salpêtrière [AP-HP]
Moranne, Olivier [Auteur]
Hôpital Universitaire Carémeau [Nîmes] [CHU Nîmes]

Titre de la revue :

Kidney International

Nom court de la revue :

Kidney Int

Date de publication :

2020-08-25

ISSN :

1523-1755

Mot(s)-clé(s) :

dialysis
registry
epidemiology
mortality
covid

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

The aim of this study was to estimate the incidence of COVID-19 disease in the French national population of dialysis patients, their course of illness and to identify the risk factors associated with mortality. Our study ...
Lire la suite >The aim of this study was to estimate the incidence of COVID-19 disease in the French national population of dialysis patients, their course of illness and to identify the risk factors associated with mortality. Our study included all patients on dialysis recorded in the French REIN Registry in April 2020. Clinical characteristics at last follow-up and the evolution of COVID-19 illness severity over time were recorded for diagnosed cases (either suspicious clinical symptoms, characteristic signs on the chest scan or a positive reverse transcription polymerase chain reaction) for SARS-CoV-2. A total of 1,621 infected patients were reported on the REIN registry from March 16th, 2020 to May 4th, 2020. Of these, 344 died. The prevalence of COVID-19 patients varied from less than 1% to 10% between regions. The probability of being a case was higher in males, patients with diabetes, those in need of assistance for transfer or treated at a self-care unit. Dialysis at home was associated with a lower probability of being infected as was being a smoker, a former smoker, having an active malignancy, or peripheral vascular disease. Mortality in diagnosed cases (21%) was associated with the same causes as in the general population. Higher age, hypoalbuminemia and the presence of an ischemic heart disease were statistically independently associated with a higher risk of death. Being treated at a selfcare unit was associated with a lower risk. Thus, our study showed a relatively low frequency of COVID-19 among dialysis patients contrary to what might have been assumed.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Date de dépôt :

2021-07-06T12:48:39Z
2024-01-31T12:55:16Z