Title :

Access to preemptive registration on the waiting list for renal transplantation: a hierarchical modeling approach

Author(s) :

Riffaut, Natacha [Auteur]
Service de Néphrologie-Dialyse-Transplantation rénale [CHU Caen]
Lobbedez, Thierry [Auteur]
Service de Néphrologie-Dialyse-Transplantation rénale [CHU Caen]
Hazzan, Marc [Auteur]
Lille Inflammation Research International Center - U 995 [LIRIC]
Bertrand, Dominique [Auteur]
CHU Rouen
Westeel, Pierre-Francois [Auteur]
CHU Amiens-Picardie
Launoy, Guy [Auteur]
Cancers et préventions
Danneville, Isabelle [Auteur]
Service de Néphrologie-Dialyse-Transplantation rénale [CHU Caen]
Bouvier, Nicolas [Auteur]
Service de Néphrologie-Dialyse-Transplantation rénale [CHU Caen]
Hurault De Ligny, Bruno [Auteur]
Service de Néphrologie-Dialyse-Transplantation rénale [CHU Caen]

Journal title :

Transplant international

Abbreviated title :

Transpl. Int.

Volume number :

28

Pages :

1066-1073

Publication date :

2015-09-01

ISSN :

0934-0874

Keyword(s) :

Mesh:Healthcare Disparities
Mesh:Cardiovascular Diseases/complications
Mesh:Male
Mesh:Health Services Accessibility
Mesh:Odds Ratio
Mesh:Kidney Failure
Mesh:Chronic/surgery*
Mesh:Middle Aged
Mesh:Kidney Transplantation/methods*
Mesh:Graft Survival
Mesh:Multivariate Analysis
Mesh:Hospitals
Mesh:France
Mesh:Female
Mesh:Adolescent
Mesh:Adult
Mesh:Humans
Mesh:Models
Mesh:Statistical
Mesh:Young Adult
Mesh:Waiting Lists*
Mesh:Treatment Outcome
Mesh:Regression Analysis
Mesh:Social Class
Mesh:Retrospective Studies
Mesh:Body Mass Index
end-stage renal disease
kidney transplantation
epidemiology and outcomes

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

Preemptive kidney transplantation is associated with both longer patient and graft survival. This study was carried out to estimate the association between the renal units and preemptive registration on the waiting list ...
Show more >Preemptive kidney transplantation is associated with both longer patient and graft survival. This study was carried out to estimate the association between the renal units and preemptive registration on the waiting list for first deceased donor renal transplantation in a French network of care. From 2008 to 2012, 1529 adult patients followed in 48 units of the French North‐West network and registered on the waiting list for a first deceased donor renal allograft were included. We used a mixed logistic regression with renal units as random‐effects term for statistical analysis. Of the 1529 patients included, 407 were placed on the waiting list preemptively. There was a significant variability across renal units (variance 0.452). In multivariate analysis, factors independently associated with preemptive registration were cardiovascular disease (odds ratio (OR) 0.57, [95% CI: 0.42–0.79]), social deprivation (OR 0.73, [95% CI 0.57–0.94]), and renal units' characteristics (ownership of the facility: academic hospital, reference—community hospital, OR 0.44, [95% CI 0.24–0.80]—private hospital, OR 0.35, [95% CI 0.18–0.69] and transplant center; P < 0.10]. Variability between renal units was reduced after taking into account their characteristics but was not influenced by patient characteristics. Preemptive registration is associated with renal units, transplant centers, and social deprivation and can be partly explained by disparities in practices.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Inserm
Université de Lille
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Research team(s) :

Immunity, inflammation and fibrsis in auto and allo-reactivity

Submission date :

2019-03-01T14:58:49Z
2020-03-12T11:18:39Z