Title :

Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway

Author(s) :

Yu, Yichi [Auteur]
Wang, Lei [Auteur]
Delguste, Florian [Auteur]
Durand, Arthur [Auteur]
Guilbaud, Axel [Auteur]
Rousselin, Clementine [Auteur]
Schmidt Ann, Marie [Auteur]
Tessier, Frederic [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Boulanger, Eric [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Nevière, Rémi [Auteur]

Journal title :

Free radical biology & medicine

Abbreviated title :

Free Radic. Biol. Med.

Volume number :

112

Pages :

397-410

Publication date :

2017-11-01

ISSN :

0891-5849

Keyword(s) :

Mesh:Diet
Mesh:High-Fat
Mesh:Mitochondrial Proteins/genetics
Mesh:Cathepsin L/metabolism
Mesh:Cardiomyopathies/drug therapy
Mesh:Mice
Mesh:Autophagy/drug effects
Mesh:Sirtuins/metabolism
Mesh:Chloroquine/pharmacology
Mesh:Lysosomes/metabolism*
Mesh:Cathepsin L/genetics
Mesh:Cardiomyopathies/chemically induced
Mesh:Mitochondria/metabolism
Mesh:Autophagy/genetics*
Mesh:Cardiomyopathies/genetics*
Mesh:Mitochondrial Dynamics/drug effects
Mesh:Dynamins/metabolism
Mesh:Mitochondrial Proteins/metabolism
Mesh:Superoxide Dismutase/metabolism
Mesh:Gene Expression Regulation
Mesh:Animals
Mesh:Myocardium/pathology
Mesh:Sirtuins/genetics
Mesh:Mitochondria/drug effects
Mesh:Mice
Mesh:Knockout
Mesh:Superoxide Dismutase/genetics
Mesh:Sirolimus/pharmacology
Mesh:Diabetes Mellitus
Mesh:Experimental/pathology
Mesh:Cardiomyopathies/pathology
Mesh:Diabetes Mellitus
Mesh:Experimental/chemically induced
Mesh:Reactive Oxygen Species/metabolism
Mesh:Receptor for Advanced Glycation End Products/genetics*
Mesh:Oxidative Stress
Mesh:Myocardium/metabolism
Mesh:Male
Mesh:Mitochondrial Dynamics/genetics*
Mesh:Dynamins/genetics
Mesh:Lysosomes/drug effects
Mesh:Diabetes Mellitus
Mesh:Experimental/genetics*
Mesh:Receptor for Advanced Glycation End Products/deficiency
Mesh:Mice
Mesh:Inbred C57BL
Mesh:Diabetes Mellitus
Mesh:Experimental/drug therapy
High fat diet
Receptor for advanced glycation end products (RAGE)
Mitochondria
Oxidative stress
Heart
Autophagy

HAL domain(s) :

Sciences du Vivant [q-bio]

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Inserm
Université de Lille
CHU Lille

Collections :

• Lille Inflammation Research International Center (LIRIC) - U995

Research team(s) :

Glycation from inflammation to aging

Submission date :

2019-03-01T15:24:28Z