Titre :

Review article: Epidemiological and animal evidence for the role of air pollution in intestinal diseases.

Auteur(s) :

Vignal, Cecile [Auteur]
Centre Lillois d'Études et de Recherches Sociologiques et Économiques (CLERSE) - UMR 8019
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Guilloteau, Eva [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Gower, Corinne [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Body-Malapel, Mathilde [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Titre de la revue :

The science of the total environment

Nom court de la revue :

Sci Total Environ

Numéro :

757

Pagination :

143718

Date de publication :

2021-02-25

ISSN :

1879-1026

Mot(s)-clé(s) en anglais :

Air Pollutants
Air Pollution
Animals
Cardiovascular Diseases
Humans
Intestinal Diseases
Particulate Matter
Colitis
Dysbiosis
Intestinal diseases

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Ambient air pollution is recognized as one of the leading causes of global burden of disease. Involvement of air pollution in respiratory and cardiovascular diseases was first recognized, and then cumulative data has ...
Lire la suite >Ambient air pollution is recognized as one of the leading causes of global burden of disease. Involvement of air pollution in respiratory and cardiovascular diseases was first recognized, and then cumulative data has indicated that the intestinal tract could be also damaged. To review and discuss the current epidemiological and animal data on the effects of air pollution on intestinal homeostasis. An extensive literature search was conducted using Google Scholar and Pubmed to gather relevant human and animal studies that have reported the effects of any air pollutant on the intestine. Exposure to several gaseous and particulate matter components of air pollution have been associated either positively or negatively with the onset of various intestinal diseases including appendicitis, gastroenteric disorders, irritable bowel syndrome, inflammatory bowel diseases, and peptic ulcers. Several atmospheric pollutants have been associated with modifications of gut microbiota in humans. Animal studies have showed that inhalation of atmospheric particulate matter can lead to modifications of gut microbiota, impairments of oxidative and inflammatory intestinal balances, and disruption of gut epithelial permeability. Overall, the literature appears to indicate that the gut is an underestimated target of adverse health effects induced by air pollution. It is therefore important to develop additional studies that aim to better understand the link between air pollutants and gastro-intestinal diseases.Lire moins >

Comité de lecture :

Oui

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
Inserm
CHU Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Date de dépôt :

2021-08-25T15:03:24Z
2021-09-01T08:01:39Z
2021-09-15T10:22:56Z
2021-09-15T10:24:49Z