Title :

[Clinical pharmacist and medication reconciliation in kidney transplantation].

Author(s) :

Flamme-Obry, Fabienne [Auteur]
Belaiche, Stephanie [Auteur]
Hazzan, Marc [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Ramdan, Nassima [Auteur]
Noel, Christian [Auteur]
Lille Inflammation Research International Center (LIRIC) - U995
Odou, Pascal [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - EA 7365
Decaudin, Bertrand [Auteur]
Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - EA 7365

Journal title :

Nephrologie & Therapeutique

Abbreviated title :

Nephrol. Ther.

Volume number :

14

Pages :

91-98

Publication date :

2018-04-01

ISSN :

1872-9177

Keyword(s) :

Drug-Related Side Effects and Adverse Reactions
Female
Humans
Kidney Transplantation
Male
Medication Errors
Medication Reconciliation
Middle Aged
Patient Discharge
Pharmacists
Renal Insufficiency
Chronic
Clinical pharmacist
Conciliation médicamenteuse
Drug related problems
Greffe rénale
Iatrogénie médicamenteuse
Kidney transplantation
Medication reconciliation
Pharmacien clinicien

HAL domain(s) :

Sciences du Vivant [q-bio]

English abstract : [en]

INTRODUCTION: Drug related problems (DRP) can lead to severe consequences in kidney recipients. The aim of the study was to assess the impact of the clinical pharmacist interventions on the incidence of DRP. METHOD: The ...
Show more >INTRODUCTION: Drug related problems (DRP) can lead to severe consequences in kidney recipients. The aim of the study was to assess the impact of the clinical pharmacist interventions on the incidence of DRP. METHOD: The number of DRP were evaluated according to 3periods: Without intervention, with medication reconciliation at admission, and with medication reconciliation at admission associated with an interview with the clinical pharmacist at discharge. RESULTS: Patients concerned were mainly men, 55years old (median age), stage3 of CKD, transplanted for less than 3months or more than 1year, with cardiovascular risk factors and receiving an average of 9drugs/day. Among the DRP, 20% were avoidable and severe in most cases. In period1, 27.7% patients had at least 1DRP, in period2, 21.3% patients had at least 1DRP, and in period3, 17.4% of patients had at least 1DRP (P=0.03). One hundred and ten patients had medication reconciliation at admission with a mean of 0.6unintentional discrepancies per patient (omission in 81% of cases). The main drugs involved concerned the digestive-metabolic (24.5%), cardiovascular (23%), and nervous (23%) system. Sixty-eight interviews at discharge were realized and revealed self-medication habits. CONCLUSION: Our study shows that medication reconciliation at admission associated with an interview with the clinical pharmacist at discharge can help to reduce DRP in kidney recipients. Further studies are needed to confirm our results.Show less >

Language :

Anglais

Audience :

Internationale

Popular science :

Non

Administrative institution(s) :

Université de Lille
CHU Lille
Inserm

Collections :

• Groupe de Recherche sur les formes Injectables et les Technologies Associées (GRITA) - EA 7365
• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Research team(s) :

Innovation/évaluation des médicaments injectables
Innovation/évaluation des dispositifs médicaux de perfusion

Submission date :

2019-02-26T17:06:57Z