Fundamental and Advanced Therapies, Vaccine Development against SARS-CoV-2.

Hudakova, N.; Hricikova, S.; Kulkarni, A.; Bhide, M.; Kontsekova, E.; Cizkova, Dasa

Type de document :

Article dans une revue scientifique: Article de synthèse/Review paper

DOI :

10.3390/pathogens10060636

PMID :

34064300

URL permanente :

http://hdl.handle.net/20.500.12210/92646

Titre :

Fundamental and Advanced Therapies, Vaccine Development against SARS-CoV-2.

Auteur(s) :

Hudakova, N. [Auteur]
Hricikova, S. [Auteur]
Kulkarni, A. [Auteur]
Bhide, M. [Auteur]
Kontsekova, E. [Auteur]
Cizkova, Dasa [Auteur]

Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192

Titre de la revue :

Pathogens

Nom court de la revue :

Pathogens

Numéro :

Date de publication :

2021-06-11

ISSN :

2076-0817

Mot(s)-clé(s) en anglais :

SARS-CoV-2
COVID-19
cytokine storm
therapy
antibodies
vaccines

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Coronavirus disease (COVID-19) caused by the SARS-CoV-2 virus has been affecting the world since the end of 2019. The severity of the disease can range from an asymptomatic or mild course to acute respiratory distress ...
Lire la suite >Coronavirus disease (COVID-19) caused by the SARS-CoV-2 virus has been affecting the world since the end of 2019. The severity of the disease can range from an asymptomatic or mild course to acute respiratory distress syndrome (ARDS) with respiratory failure, which may lead to death. Since the outbreak of the pandemic, scientists around the world have been studying the genome and molecular mechanisms of SARS-CoV-2 infection to develop effective therapies and prevention. In this review, we summarize the progressive development of various treatments and vaccines as they have emerged, a year after the outbreak of the pandemic. Initially for COVID-19, patients were recommended drugs with presumed antiviral, anti-inflammatory, and antimicrobial effects that were previously used to treat other diseases. Thereafter, therapeutic interventions were supplemented with promising approaches based on antibodies, peptides, and stem cells. However, licensed COVID-19 vaccines remain the most effective weapon in combating the pandemic. While there is an enormous effort to enhance the vaccination rate to increase the entire population immunity, the production and delivery of vaccines is becoming limited in several countries. In this regard, there are new challenges needing to be addressed by combining non-pharmacological intervention with effective therapies until vaccination is accessible to all.Lire moins >

Comité de lecture :

Oui

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

Université de Lille
Inserm
CHU Lille

Collections :

Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192

Date de dépôt :

2023-12-13T04:55:48Z
2024-01-31T10:45:37Z

Fichiers

pathogens-10-00636-v3.pdf
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Ce document est diffusé sous licence Attribution 3.0 United States

Numéro de version	Lien	Date de modification
2	20.500.12210/92646*	2024-01-31T10:43:47Z
1	20.500.12210/92646.1	2023-12-13T04:55:48Z

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